Chewing your food properly can boost your mouth’s immune system to protect you against illness.
Highlights
- Chewing food properly, can improve the immune system.
- A specific type of immune cell, the Th17 cell, is stimulated during chewing.
- Th17 cell is important in protecting against bacterial and fungal infections that are commonly found in the mouth .
The immune cell is important in protecting against bacterial and fungal infections that are commonly found in the mouth . Although it has long been known that the nutrients from food can support a healthy immune system the findings establish that the action of eating itself is important too.
In other parts of the body, such as the gut and skin, Th17 cells are stimulated by the presence of friendly bacteria; it was previously assumed this was the case in the mouth.
Lead researcher and biologist Dr Joanne Konkel, from The University of Manchester, said, “The immune system performs a remarkable balancing act at barrier sites such as the skin, mouth and gut by fighting off harmful pathogens while tolerating the presence of normal friendly bacteria.” “Our research shows that, unlike at other barriers, the mouth has a different way of stimulating Th17 cells: not by bacteria but by mastication. Therefore mastication can induce a protective immune response in our gums”.
However, the team found that damage caused by the abrasion of chewing induced factors from the gums that could activate the same pathways as friendly bacteria and act upon Th17 cells.
In the journal Immunity, the team show that they were able to stimulate increases in Th17 cells in mice by merely changing the hardness of their food, proving that mastication was the critical factor.
She added: “Importantly, because inflammation in the mouth is linked to development of diseases all around the body understanding the tissue-specific factors that regulate immunity at the oral barrier could eventually lead to new ways to treat multiple inflammatory conditions”
Reference
- Nicholas Dutzan et al., On-going Mechanical Damage from Mastication Drives Homeostatic Th17 Cell Responses at the Oral Barrier, Immunity (2017) http://dx.doi.org/10.1016/j.immuni.2016.12.010
Source-Medindia