Autism is a neurodevelopmental disorder that occurs in 1 in 160 children worldwide.
Highlights:
Scientists have discovered 60 new genes linked to autism spectrum disorder (ASD). This discovery can help in providing clues to the causes of autism, reveals a new study led by Columbia researchers.//
“Overall, the genes we found may represent a different class of genes that are more directly associated with the core symptoms of ASD than previously discovered genes,” says Wendy Chung, MD, PhD, the Kennedy Family Professor of Pediatrics and chief of clinical genetics in the Department of Pediatrics at the Columbia University Vagelos College of Physicians and Surgeons. The findings were published in Nature Genetics.- About 60 new genes have been discovered by scientists
- Autism is a neurodevelopmental disorder that occurs in 1 in 160 children worldwide
- Discovery of these new genes can help understand the biology of the brain and behavior of autistic children better
World Autism Day 2022 � �Inclusive Quality Education for All�
World Autism Day is commemorated every April to raise global awareness of autism and promote inclusivity for all those affected with autism.
World Autism Day is commemorated every April to raise global awareness of autism and promote inclusivity for all those affected with autism.
‘Identification of these new 60 autism genes can help scientists understand the function of the brain better.’
Discovery of Hidden Autism Genes
Several genes have been previously linked to autism and as a group is responsible for about 20% of all cases. Most individuals who carry these genes have profound forms of autism and additional neurological issues, such as epilepsy and intellectual disability.To uncover hidden autism genes that can explain the majority of cases, the researchers tapped into data from nearly 43,000 people with autism, including 35,000 individuals from the SPARK autism research study of the Simons Foundation.
Five of the genes identified by the new study have a more moderate impact on autism characteristics, including cognition than previously discovered genes.
Rare Genetic Mutations Predict Intellectual Disability in Autism Spectrum Disorder (ASD)
Novel computational model identifies the genes linked to autism that helps in predicting the level of intellectual disability in people with autism spectrum disorders (ASD).
Novel computational model identifies the genes linked to autism that helps in predicting the level of intellectual disability in people with autism spectrum disorders (ASD).
The five newly identified genes also explain why autism often seems to run in families. Unlike previously known autism genes due to de novo or new mutations, genetic variants in the five new genes were often inherited from the participant’s parents.
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Autism Risk Can Now be Predicted by Sperm Analysis
Autism risk can be accurately predicted before birth by detecting any de novo mutations in the father’s sperms. The presence of these mutations significantly increases the risk of autism in future children.
Autism risk can be accurately predicted before birth by detecting any de novo mutations in the father’s sperms. The presence of these mutations significantly increases the risk of autism in future children.
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AI Algorithm Used to Find Causes of Autism Linked to Our �Junk� DNA
Using Artificial Intelligence (AI), a team of researchers has shown that mutations in ‘junk’ DNA can cause autism. Junk DNA mutations affect the expression of genes in the brain including those genes directly responsible for neurodevelopment and neuron migration.
Using Artificial Intelligence (AI), a team of researchers has shown that mutations in ‘junk’ DNA can cause autism. Junk DNA mutations affect the expression of genes in the brain including those genes directly responsible for neurodevelopment and neuron migration.
