Indians eat more fiber-rich plant based diet than people in the Western countries, reducing their risk of gut-related problems such as inflammatory bowel diseases like crohn's disease.
Highlights:
Indians who consume a fiber-rich diet are at a lower risk of developing gut-related problems like crohn's disease, colitis irritable bowel syndrome (IBS) and colon cancer, reveals a new research.//
The international study, including researchers from the Indian Institute of Science Education and Research (IISER)- Bhopal, sought to understand the relationship between gut bacteria and inflammatory diseases. - Indians eat more fiber-rich diet than people in the Western countries
- Indians gut microbiome has the highest abundance of the Prevotella genus of bacteria
- New probiotics and prebiotics can be developed to prevent any gut-related problems
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A diet rich in fiber promotes the growth of specific bacteria in the gut that can control blood glucose levels and thereby help treat and manage type 2 diabetes.
A diet rich in fiber promotes the growth of specific bacteria in the gut that can control blood glucose levels and thereby help treat and manage type 2 diabetes.
‘The new insights observed in this study can help develop new probiotics and prebiotics to prevent any gut-related problems.’
"Increased intake of carbohydrate in the form of fiber such as wheat, vegetables, fruits and lentils, mostly found in Indian diet lowers the incidence of IBD, crohn's disease, colitis, colorectal cancer, etc., than western diets that are generally meat-based," lead author Dr Vineet K. Sharma, Associate Professor, Department of Biological Sciences, IISER Bhopal, told IANS. The human gut contains 300-500 types of bacteria that are necessary for our survival. These bacteria help in digestion, protect us from infections and even produce essential vitamins and neurochemicals.
Depending on the kind of bacteria that dominates the gut, human beings are generally classified into three "enterotypes" -- Prevotella, Bacteroides or Ruminococcus.
Fiber can Prevent Deterioration of Inner Colon Mucus Layer
Low-fiber diet can alter the composition of colonic microbiota, increases bacterial penetrability and reduces the growth rate of the inner mucus layer.
Low-fiber diet can alter the composition of colonic microbiota, increases bacterial penetrability and reduces the growth rate of the inner mucus layer.
The 200 gut samples from India were taken from people from several locations in -- Madhya Pradesh, Delhi-NCR, Rajasthan and Maharashtra, Bihar, and Kerala. It is also the largest gut metagenome study from India, as most such studies are largely based on the Western population.
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This bacterium was also found to dominate the guts of other populations that consume a carbohydrate and fiber-rich diet, such as the Italian, Madagascarian, Peruvian, and Tanzanian. But, the gut microbiomes of people from Western countries like the US are dominated by Bacteroides.
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Whole Grains can Reduce the Risk of Developing Colorectal Cancer
Dietary fiber, especially from whole grains and cereals, is associated with a decreased risk of colorectal cancer.
Dietary fiber, especially from whole grains and cereals, is associated with a decreased risk of colorectal cancer.
It is thus logical that this type of bacteria predominates the gut microbiome of the healthy Indian and non-western population that consumes a diet rich in plant-carbohydrates and fibers, Sharma explained.
"The proportion of P.copri in Indians is 30 percent and can reach up to 60-70 percent. Of the more than 1200 species of Prevotella, P.copri is the most abundant in Indian human gut," Sharma told IANS.
On the other hand, the guts of Western population were found to have other Prevotella species such as P. intermedia and P. nigrescens. These bacteria are usually found in the mouth, which points to a mouth-gut axis. These bacterial species are inflammatory and have high virulence and antibiotic resistance genes, making the Western population more susceptible to gut inflammatory diseases.
"Our insights would help in the development of new probiotics and prebiotics for different health-related conditions associated with the gut which is much needed for non-western populations," Sharma said.
Source-IANS
