According to a recent study, candesartan does not produce beneficial effects in stroke patients and in fact may cause harm.

Candesartan is a blood pressure lowering drug belonging to the group of angiotensin II receptor blockers. A recent study was conducted to find out if candesartan provides benefit in stroke patients by reducing blood pressure. The patients were followed to determine if they experienced changes in functional outcomes or if they suffered from further complications like stroke, heart attack and death.
The researchers found that reducing blood pressure does not provide beneficial effects in these patients. In fact, it may have some harmful effect especially in functional outcomes.
Further studies using different blood pressure lowering drugs may be required to establish their role in the treatment of stroke.
Reference
- Harrison’s Principles of Internal Medicine 17th edition
- The angiotensin-receptor blocker candesartan for treatment of acute stroke (SCAST): a randomised, placebo-controlled, double-blind trial. The SCAST Study Group. The Lancet, Volume 377, Issue 9767, Pages 741 - 750, 26 February 2011
Source-Medindia