Health outcomes in patients with kidney disease can be predicted with the help of different symptom trajectories.
Highlights:
One-third of people with various degrees of chronic kidney disease (CKD), not receiving dialysis, who responded to annual questionnaires about their symptoms might have a ‘worse symptom score and deteriorating trajectory’ of symptoms. These patients had particularly significant risks of subsequently needing dialysis and of passing away before starting treatment.
The Kidney Disease Quality of Life-36 questionnaire was completed by 2,787 persons in France who had CKD but weren’t receiving dialysis for the study by Moustapha Faye, MD (CHRU Nancy, Université Cheikh Anta Diop de Dakar), and his colleagues. - The prevalence of each symptom ranged from 24% (chest discomfort) to 83% (fatigue) among people with various degrees of chronic kidney disease who were not receiving dialysis, and 98% of participants reported having at least one symptom
- Patients with a ‘worse symptom score and worsening trajectory’ of symptoms were more likely to require dialysis in the future and to pass away before starting treatment
Diabetic Kidney Disease - Symptoms, Signs, Causes, Diagnosis, Stages & Treatment
Diabetic nephropathy refers to kidney damage due very high levels of blood sugar levels in diabetics.
Diabetic nephropathy refers to kidney damage due very high levels of blood sugar levels in diabetics.
‘Different symptom trajectories can be used to predict health outcomes in people with renal disease.’
Symptoms of Chronic Kidney Disease Patients
98% of participants reported experiencing at least one symptom, with the prevalence of each symptom ranging from 24% (chest discomfort) to 83% (fatigue). 690 people began kidney replacement therapy (KRT), such as dialysis, after a median follow-up of 5.3 years, while 490 participants passed away before KRT.Symptom Trajectory Profile in Kidney Disease Patients
The team found two types of symptom trajectory profiles: a ‘worse symptom score and worsening trajectory’ in 31% of participants, which was defined by a low initial symptom score that got worse by more than 10 points (on a scale of 0-100) over time, and a ‘better symptom score and stable trajectory’ in 69% of participants, which was defined by a high initial score that stayed stable over time.Better quality of life, more risk factors for CKD progression at baseline, a higher risk of KRT, and a higher chance of death before KRT were all present among participants in the group of ‘worse symptom score and worsening trajectory’ than in other people.
Renal Osteodystrophy | Chronic Kidney Disease - Mineral and Bone Disorder - Symptoms, Signs, Diagnosis & Treatment
Renal osteodystrophy is mineral bone disorder due to prolonged kidney damage and failure. There is imbalance in the levels of calcium, phosphorus, parathyroid hormone, and vitamin D.
Renal osteodystrophy is mineral bone disorder due to prolonged kidney damage and failure. There is imbalance in the levels of calcium, phosphorus, parathyroid hormone, and vitamin D.
Source-Medindia
Drug-Induced Kidney Disease | Nephrotoxicity
Drug-induced nephrotoxicity is caused by nephrotoxic drugs or toxins which damage kidneys and can lead to nephritis or renal toxicity. The causative drug must be identified and its use must be avoided which can otherwise lead to high levels of toxins and severe damage to kidneys.
Drug-induced nephrotoxicity is caused by nephrotoxic drugs or toxins which damage kidneys and can lead to nephritis or renal toxicity. The causative drug must be identified and its use must be avoided which can otherwise lead to high levels of toxins and severe damage to kidneys.
Anemia in Children with Chronic Kidney Disease
A recent review listed out the causes, risk factors, complications and treatment of anemia in children with chronic kidney disease.
A recent review listed out the causes, risk factors, complications and treatment of anemia in children with chronic kidney disease.
