Kidney Stones can be Tackled With Drug Used To Treat Enlarged Prostate

New research shows that people suffering from kidney stones can be treated using Tamsulosin, the drug that is usually used to treat an enlarged prostate.

Highlights

Kidney stones are a common problem affecting millions of people worldwide.
Kidney stones can range in size from a grain of sand to a pearl or even larger, and can be excruciating to pass through the urinary tract.
Tamsulosin is normally used to treat an enlarged prostate.
Researchers found that the treatment using Tamsulosin could also assist the passage of large kidney stones in the urine.

Patients suffering from kidney stones could soon get relief, with researchers discovering a prostrate treatment can also help ease the painful condition.

Up to 15% of the Australian adult population and 1 in 11 people in the United States suffer from kidney stones.

Tests for Kidney Stones
Kidney stones are diagnosed using radiological tests like plain x-ray KUB, CT scan, ultrasound and intravenous pyelography, blood tests and urine tests.

‘Using Tamsulosin can help patients with large stones to avoid complicated treatments including surgeries, and this has potential to improve care and reduce costs.’

Kidney stones can range in size from a grain of sand to a pearl or even larger, and can be excruciating to pass through the urinary tract.

Patients with kidney stones were treated with the drug Tamsulosin in an Emergency Medicine Foundation Australasia (EMF) funded clinical trial run across five Australian hospital emergency departments.

Trial leader and specialist emergency medicine physician at The Townsville Hospital, Dr Jeremy Furyk, said Tamsulosin was normally used to treat an enlarged prostate, but the research team found the treatment could also assist the passage of large kidney stones in the urine.

Gut Bacteria Oxalobacter Formigenes Associated With Reduced Risk Of Kidney Stones
Factors secreted by Oxalobacter formigenes reduce urinary secretion of oxalate thereby lowering the risk of kidney stones.

"Kidney stones are a bit of a mystery, occur frequently in the community and generally affect young, healthy adults," Dr Furyk said.

It can be extremely painful to pass these jagged little crystallized minerals and it is very common for sufferers to go to an emergency department for treatment.

Kidney Stones Increasing Among Youth, Especially in Females and African-Americans
Kidney stones are increasing, particularly among adolescents, females, and African-Americans in the U.S., a striking change from the historic pattern.

Among the more than 400 patients in the trial, those who received Tamsulosin passed their large kidney stones more often than the placebo group.

"This means patients with large stones might not need more complicated treatments including surgeries, and this has potential to improve care and reduce costs. We're very excited because Tamsulosin treatment may also allow patients to be treated closer to home rather than needing referral to a major centre."Dr Furyk said.

Common Genetic Link Identified In Prostate Cancer And Ewing�s Sarcoma
Researchers find a common genetic link between molecular mechanisms in prostate cancer and Ewing's sarcoma.

EMF Australasia awarded more than $270,000 to support Dr Furyk's research, through its Queensland Research Program, which is funded by the Queensland Government Department of Health.

EMF Australasia Chair, Associate Professor Sally McCarthy said this research had the potential to help millions of Australians suffering with this extremely painful condition.

It may also have implications for patients living in rural and regional areas, where access to urologists - the specialist doctors who treat this condition - can be limited.

Source-Medindia