Humans to regrow lost teeth naturally.
- Scientists discovered a drug that activates dormant tooth buds by blocking the USAG-1 protein
- Animal trials showed success, and human clinical trials are now underway in Japan
- This breakthrough could eliminate the need for dentures and implants by 2030
Advances in tooth agenesis and tooth regeneration
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Humans may carry the hidden ability to grow a third set of teeth—naturally! #toothregrowth #medindia’





Science of Tooth Regrowth
Humans could naturally grow a third set of teeth. Oral surgeon Dr. Katsu Takahashi's team discovered a hidden potential in our biology to regenerate teeth. They discovered that USAG-1, a protein that suppresses dormant tooth buds, could be used to stimulate tooth regrowth in mice and ferrets.
From Discovery to Human Trials
A new drug developed at Kyoto University has the potential to offer a natural and permanent solution to tooth loss. The drug works by blocking USAG-1 protein, allowing dormant tooth buds to develop.The first phase of trials will involve adults with lost molars, followed by children born with missing teeth. The research team aims to make the treatment widely available by 2030, with an estimated cost of $9,800 per procedure.
Future of Dentistry and Its Impact
A new drug neutralizes the USAG-1 protein, allowing dormant tooth buds to develop into full teeth. This could revolutionize dentistry by providing a permanent and natural solution to tooth loss, especially beneficial for anodontia (rare genetic condition characterized by the complete absence of teeth) patients. The treatment could reduce dental prosthetics and offer a more comfortable, lasting solution. The cost is around $9,800.Reference:
- Advances in tooth agenesis and tooth regeneration - (https://pmc.ncbi.nlm.nih.gov/articles/PMC9931762/)
Source-Medindia