Weaning to an extensively hydrolyzed casein formula during infancy did not result in a reduction in the incidence of type 1 diabetes.
Highlights
- Delaying the exposure to complex foreign proteins such as cow's milk proteins would not decrease the risk of diabetes.
- A study was done regarding the potential role of //cow's milk formula in the development of type 1 diabetes.
- After 10 years of follow-up, it was found that early exposure to cow’s milk may not cause type 1 diabetes.
Type 1 Diabetes in Children - Causes, Symptoms, Diagnosis, Complications & Treatment
Type 1 diabetes is a condition most common in children in which the pancreas stops producing and releasing the hormone insulin that controls blood sugar levels.
Type 1 diabetes is a condition most common in children in which the pancreas stops producing and releasing the hormone insulin that controls blood sugar levels.
‘Infants with a family member affected by type 1 diabetes and with genetic risk for type 1 diabetes may not prevent type 1 diabetes by avoiding the exposure to complex foreign proteins.’
In 2002, the research team for TRIGR (Trial to Reduce IDDM in the Genetically at Risk), led in the U.S. by principal investigator Dorothy Becker, M.D., professor of pediatrics at Children's Hospital and the University of Pittsburgh School of Medicine, embarked on a large-scale study of 2,159 infants with a family member affected by type 1 diabetes and with genetic risk for type 1 diabetes to find out whether delaying the exposure to complex foreign proteins such as cow's milk proteins would decrease the risk of diabetes. After breastfeeding, infants were either weaned to a special formula (extensively hydrolyzed casein formula), with the cow's milk proteins split into small peptides (small pieces of the protein), or a regular cow's milk-based formula with intact cow's milk proteins.
Infants were fed the study formula for at least two months until the age of 6 to 8 months and at the same time were given no cow's milk proteins from any other food sources. The children were followed for at least 10 years to determine which children developed diabetes.
Type 1 Diabetes - Treatment and Management
An overview of type 1 diabetes, its contributing factors, management and adopting a healthy lifestyle to cope with it.
An overview of type 1 diabetes, its contributing factors, management and adopting a healthy lifestyle to cope with it.
"After more than 15 years of effort, this study puts to rest the controversy regarding the potential role of cow's milk formula in the development of type 1 diabetes," said Becker. "This once more shows us that there is no easy way to prevent type 1 diabetes. Accordingly, there is no evidence to revise the current dietary recommendations for infants at high risk for type 1 diabetes. We need to chip away at our research efforts around the world to find interventions that may change the pre-diabetes course. Ongoing work of our study is doing just that."
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Diabetes Essentials: Types, Complications, Management & Treatment
Diabetes is a metabolic disease caused by insulin deficiency that leads to high blood sugar levels and several associated complications if left untreated.
Diabetes is a metabolic disease caused by insulin deficiency that leads to high blood sugar levels and several associated complications if left untreated.
- Dorothy Becker et al., ‘Modifying baby formula doesn't prevent type 1 diabetes in children.’ Journal of the American Medical Association. (2017).
Source-Medindia
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Pancreas transplant is a surgical procedure involving the replacement of a dysfunctional pancreas in a person with Type 1 or insulin-dependent diabetes.
Pancreas transplant is a surgical procedure involving the replacement of a dysfunctional pancreas in a person with Type 1 or insulin-dependent diabetes.
