UC Davis researchers have developed a way to use the empty shell of a Hepatitis E virus to carry vaccines or drugs into the body.
No Proof That Radiation From X-Rays, CT Scans can Cause Cancer
The widespread belief that radiation from X-rays, CT scans and other medical imaging can cause cancer is based on an unproven, decades-old theoretical model.
The widespread belief that radiation from X-rays, CT scans and other medical imaging can cause cancer is based on an unproven, decades-old theoretical model.
‘Hepatitis E virus-like particles could be used as vaccines or anti-cancer drugs that are delivered through food or drink. The idea is that you would drink the vaccine, and after passing through the stomach the virus-like particles would get absorbed in the intestine and deliver it to the target organ.’
Such particles could be used as vaccines that are delivered through food or drink. The idea is that you would drink the vaccine, and after passing through the stomach the virus-like particles would get absorbed in the intestine and deliver vaccines to the body. But the particles could also be used to attack cancer. Stark and Cheng did some tinkering with the proteins, so that they carry sticky cysteine amino acids on the outside. They could then chemically link other molecules to these cysteine groups.
They worked with a molecule called LXY-30, developed by researchers at the UC Davis Comprehensive Cancer Center, which is known to stick to breast cancer cells. By using a fluorescent marker, they could show that virus-like particles carrying LXY-30 could home in on breast cancer cells both in a laboratory dish and in a mouse model of breast cancer.
Nutrient Deprivation Kills Kidney Cancer Cells, Significantly Delays Tumor Growth
By depriving cancer cells of the amino acid cystine, the researchers were able to trigger necrosis in mouse models of renal cell carcinoma.
By depriving cancer cells of the amino acid cystine, the researchers were able to trigger necrosis in mouse models of renal cell carcinoma.
Source-Eurekalert
Promising Peptide Compounds Against a Cancer Target
Advances in new treatments for diseases, including cancer, come about from innovative research with therapeutic potential.
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Being diagnosed with cancer at a prime age with flying dreams and a family to look after can be earth-shattering for most people.
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