Prevalence of Opioid Use By SSDI Recipients is High: Medical Care Report

Prevalence of opioid use is over 20 percent and rising, and more than 40 percent of SSDI recipients take opioid pain relievers, reports a study in the September issue of Medical Care.

Prevalence of opioid use is over 20 percent and rising, and more than 40 percent of Social Security Disability Insurance (SSDI) recipients take opioid pain relievers, reports a study in the September issue of Medical Care. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

The high proportion of SSDI recipients who are chronic opioid users—in many, at high and very high daily doses—"is worrisome in light of established and growing evidence that intense opioid use to treat non-malignant [non-cancer] pain may not be effective and may confer important risk," write Dr Nancy Elizabeth Morden and colleagues of the Dartmouth Institute for Health Policy & Clinical Practice, Lebanon, N.H.

Opioid-Induced Hyperalgesia (OIH): An Emerging Treatment Challenge
Opioid induced hyperalgesia is defined as increased nociceptive sensitization caused by exposure to opioids.

Rising Prevalence of Opioid Use by SSDI Recipients The researchers analyzed trends in use of prescription opioids (morphine-related drugs) among disabled Medicare beneficiaries under age 65 between 2007 and 2011. Nearly all under-65 Medicare beneficiaries are SSDI recipients; patients who go on SSDI are eligible for Medicare after two years.

Consistent with reports of an "opioid epidemic" in the United States, the results showed high and rising prevalence of opioid use by SSDI recipients. The percentage of beneficiaries taking opioids increased from 2007 through 2010. In 2011, the most recent year with available data, prevalence dipped slightly to 43.7 percent.

The percentage of these beneficiaries with chronic opioid use rose steadily, from 21.4 percent in 2007 to 23.1 percent in 2011. Chronic opioid users received numerous opioid prescriptions—at least six and generally 13 per year—typically prescribed by multiple doctors. Women were at greater risk of becoming chronic opioid users than men.

Tiotropium Shows Potential as an Adjunctive Therapy for Asthma
Adding tiotropium to the combination therapy may delay exacerbation and provide sustained bronchodilation in asthma patients without heart disease.

Among chronic opioid users, the average "morphine equivalent dose" (MED) also dipped in 2011. Still, nearly 20 percent of chronic users were taking a dose of at least 100 milligrams MED, while ten percent were taking 200 milligrams. "Opioid use of this intensity has been associated with risk of overdose death in the general US population and more specifically in disabled workers," Dr Morden and colleagues write.

With Wide Regional Variations in Opioid Prescribing The researchers also found variations in opioid use across US health care regions. The regional prevalence of opioid use among SSDI recipients ranged from 33.0 to 58.6 percent; chronic use ranged from 14.0 to 36.6 percent. Drug dosage and specific opioids prescribed also varied by region.

Drug Detox – Alcohol, Opioid, Nicotine Detoxification
Drug detoxification (or drug detox) is a process that helps drug addicts to give up drugs with less or no withdrawal symptoms.

The high prevalence and intensity of opioid use among SSDI recipients parallels the preponderance of musculoskeletal disorders, such as back pain—some type of musculoskeletal condition was present in 94 percent of chronic opioid users. The researchers also note the high rate of depression, 38 percent, among patients taking chronic opioids.

Dr Morden and colleagues voice concern about the trends in opioid use by SSDI recipients—particularly chronic use at potentially hazardous doses. "We are not suggesting that all chronic opioid use is more harmful than beneficial," they write, "but rather that the common and increasing chronic use we observed seems inconsistent with the uncertainties surrounding such prescribing practice."

Opioids in Pregnancy: Are They Safe?
Researchers suggest that opioids should be used with caution in pregnant women.

The regional variation identified in the study "shows a lack of standardized approach and reveals regions with mean MED levels associated with overdose risk," the researchers add. They urge further studies to assess the clinical outcomes of opioid use by under-65 disabled workers and factors associated with chronic opioid use. They also call for the development of policies and programs that balance safety with high-quality pain management for this complex group of patients.

Source-Eurekalert