About DNA Fingerprinting
DNA fingerprinting is a technique which helps forensic scientists and legal experts solve crimes, identity thefts, legal suits and terrorism cases.
DNA fingerprinting is a technique which helps forensic scientists and legal experts solve crimes, identity thefts, legal suits and terrorism cases.
‘DNA repair mechanisms can be studied using advanced genome editing — prime editing (an improved variant of the CRISPR/Cas system).’
"Depending on the type of DNA damage, a cell has different cellular repair mechanisms. To find out which of these are active in prime editing, we performed a targeted genetic screening for DNA repair factors covering all known repair pathways," say the study authors. "Our results show that the DNA repair pathway, known as mismatch repair, influences prime editing outcomes". "By removing the activity of the mismatch repair pathway from a cell, we show that the efficiency of prime editing can be increased, and its accuracy improved," says Joanna Loizou, group leader at the Center for Cancer Research at MedUni Vienna and CeMM adjunct principal investigator.
Source-Medindia
DNA Repair Boosts Prospects for Gene Editing
A new method Repair-seq developed by researchers reveals in exquisite detail how genome editing tools work.
A new method Repair-seq developed by researchers reveals in exquisite detail how genome editing tools work.
DNA Binding - a Long-term Commitment or Brief Relationship?
The new study result contradicts our current understanding of gene regulation - the genetic code affects how often the proteins bind, but not for how long.
The new study result contradicts our current understanding of gene regulation - the genetic code affects how often the proteins bind, but not for how long.
Genetic Counselling - Steps GeneticInheritance Risks Conclusion
Encyclopedia section of medindia gives general info about Genetic counseling
Encyclopedia section of medindia gives general info about Genetic counseling
