Hope of New Treatments for Chronic Inflammatory Disease

New discovery made by an International team of researchers has raised hopes of better and improved treatments for chronic inflammatory diseases like psoriasis and asthma.

They have identified a new type of immune cell that can be out of control in certain inflammatory diseases and worsen symptoms.

Asthma - Factors, Common Allergens, Diagnosis, Treatment, Support Groups, FAQs
It's a lung condition characterized by inflammation of the bronchi and constriction of the airways that result in coughing, wheezing or breathlessness. Allergy and other airway irritants can trigger it

The new cell called Th22 is a kind of T-helper cell. These are white blood cells that help to activate other immune cells when the body is infected by a pathogen, such as a virus or bacterium. They also control inflammation in the body to help fight off infection.

The research team from Imperial College London, the Istituto Dermopatico dell'Immacolata in Rome and the Centre of Allergy and Environment have found that

Th22 cells play a special role in overseeing and coordinating immune cells that cause inflammation.

In chronic and allergic inflammatory diseases like psoriasis and allergic eczema, Th22 cells appear to be malfunctioning, leading to excessive inflammation, which can worsen symptoms.

The researchers hope that it may ultimately be possible to treat chronic skin and possibly also airway diseases by targeting Th22 cells with new drugs.

Allergy - Causes - Symptoms - Diagnosis - Treatment - FAQs - Videos
An allergy is a hypersensitive disorder of immune system. Substances that often cause allergic reactions are pollen, dust mites, mold spores, pet dander, food, insect stings and medicines.

"We are seeing an increase in chronic diseases like skin and airway disease because of changes in people's lifestyles," said Dr Carsten Schmidt-Weber, one of the lead authors of the study from the National Heart and Lung Institute at Imperial College London.

"These diseases can have a big impact on people's lives and patients can face a constant battle to keep their symptoms at bay.

Atopic Dermatitis / Eczema - Causes - Symptoms - Diagnosis - Treatment - FAQs
Atopic dermatitis is an inflammatory, non-contagious, chronic skin disorder that involves scaly and itchy rashes. It is also called eczema, dermatitis or atopy.

"We are very excited about discovering this new subset of T-helper cells, as we believe it could provide a new target for the treatment of chronic inflammatory diseases in the future," Schmidt-Weber added.

The study appears in Journal of Clinical Investigation.

Source-ANI
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