Inhaled Vaccines Offer Better COVID-19 Protection Than Nasal Sprays

Inhaled COVID-19 vaccines bypass the nasal passage and deliver deep into the airway, where they can induce a broadly protective immune response.

Comparing respiratory vaccine-delivery systems has confirmed that inhaled aerosol vaccines provide far better protection and stronger immunity than nasal sprays.

COVID-19 Vaccine can Reach Faster Through Nose

While nasal sprays reach primarily the nose and throat, inhaled aerosols bypass the nasal passage and deliver vaccine droplets deep in the airway, where they can induce a broadly protective immune response.

For the study published in the journal Frontiers in Immunology, researchers used a tuberculosis vaccine to compare delivery methods by measuring the distribution of droplets, immune responses, and potency in animals.

COVID-19 Vaccination in India: Issues and Challenges
India’s COVID-19 vaccination program has been launched. It currently uses the vaccines Covishield and Covaxin. There are some issues and challenges that need to be overcome in order to vaccinate all Indians.

‘New evidence supports the development of inhaled aerosol delivery over nasal spray for human vaccination against respiratory infections including TB, COVID-19 and influenza.’

When the vaccine was delivered directly into the lungs it stimulated stronger immune responses, providing much better protection from TB.

“Infections in the upper respiratory tract tend to be non-severe. In the context of infections caused by viruses like influenza or SARS-CoV-2, it tends to be when the virus gets deep into the lung that it makes you sick,” explains Matthew Miller, a co-author of the study who holds the Canada Research Chair in Viral Pandemics at McMaster University.

The immune response you generate when you deliver the vaccine deep into the lung is much stronger than when you only deposit that material in the nose and throat because of the anatomy and nature of the tissue and the immune cells that are available to respond are very different.

COVID-19 Vaccine: Myths and Facts
Debunking several misconceptions or myths that have surfaced regarding covid vaccination is important and focus on the facts related to COVID-19 vaccines.

This study for the first time provides strong preclinical evidence to support the development of inhaled aerosol delivery over nasal spray for human vaccination against respiratory infections including TB, COVID-19 and influenza.

More than 6.3 million people died during the COVID-19 pandemic, and respiratory infections remain a significant cause of illness and death throughout the world, driving an urgent and renewed worldwide effort to develop vaccines that can be delivered directly to the mucous lining of the respiratory tract.

Wearing Mask in an Unmasked Crowd Can Still Protect You from COVID-19
Are you tired of wearing a face mask? You should still wear a mask that protects you and others from COVID-19 infection and to prevent virus transmission.

Scientists at McMaster University have developed a unique inhaled form of COVID-19 vaccine and believe this deep-delivery method offers the best defense against the current and future pandemics.

A phase 1 clinical trial is currently underway to evaluate the inhaled aerosol vaccine in healthy adults who had previously received two or three doses of an injected COVID-19 mRNA vaccine.

Is �COVID Teeth� a Possible Symptom of the Fourth Wave of COVID-19?
Are new COVID-19 variants showing teeth and gum problems as early signs of COVID-19 infection? Experts warn not to ignore oral health.

Source-Medindia