Bisphosphonates are effective at suppressing the elevated bone turnover and bone pain that are characteristic of Paget's disease of bone.
Single Dose IV Medication as First-Choice Treatment for Paget's Disease
The Endocrine Society issued a Clinical Practice Guideline (CPG) for the diagnosis and treatment of Paget's disease of the bone.
The Endocrine Society issued a Clinical Practice Guideline (CPG) for the diagnosis and treatment of Paget's disease of the bone.
‘Long-term intensive bisphosphonate therapy, for patients with Paget's disease of bone, conferred no clinical benefit over giving bisphosphonates only when patients felt bone pain.’
Although bisphosphonates are effective at suppressing the elevated
bone turnover and bone pain that are characteristic of Paget's disease
of bone, the study's results suggest that the drugs should be used to
control symptoms rather than to suppress bone turnover. "This is an important study since it shows that clinicians involved in the management of Paget's disease should be treating the patient and not biochemical markers of bone turnover," said Dr. Stuart Ralston, senior author of the Journal of Bone and Mineral Research study. "Bisphosphonates are effective drugs for the treatment of Paget's but our study suggests that striving to normalize biochemical markers may be harmful."
Source-Eurekalert
Measles Gene Could Be Key To Paget's Disease
A gene from the measles virus could be playing a key role in the development of Paget’s disease of bone, according to a team of US researchers.
A gene from the measles virus could be playing a key role in the development of Paget’s disease of bone, according to a team of US researchers.
Blame Your Genes for Bone Disease
After 10-years of research the scientists have found several new genes which are responsible for the inheritance of Paget's disease, a bone condition that affects 5% people over 55-years.
After 10-years of research the scientists have found several new genes which are responsible for the inheritance of Paget's disease, a bone condition that affects 5% people over 55-years.
About Pagets And Jaw Bone Diseases
Osteitis deformans, or Pagets disease of the bone, is the deformity of the bone. Symptoms include severe bone pain, bowing of legs, deafness, facial paralysis and spinal deformities.
Osteitis deformans, or Pagets disease of the bone, is the deformity of the bone. Symptoms include severe bone pain, bowing of legs, deafness, facial paralysis and spinal deformities.
