Disruption in the epigenetic mechanisms that control the activity of different genes was found to lead to diseases such as type 2 diabetes and obesity.
Epigenetics
In the recent years ‘epigenetics’ represents inheritable changes in gene expression that do not include DNA alterations.
In the recent years ‘epigenetics’ represents inheritable changes in gene expression that do not include DNA alterations.
‘Epigenetic mechanisms play an important role in disease development. ’
This review summarises the role of epigenetic changes in different human tissues of relevance for metabolism, for example, in adipose tissue, skeletal muscle, pancreatic islets (which, among other things, contain the insulin-producing cells), liver and blood, linked to obesity and type 2 diabetes. "Similarly, the epigenetic patterns are affected by disease. Variations in genetic material (DNA), age, exercise and diet also have an impact on epigenetic variation", says Charlotte Ling, professor and pioneer in the field of epigenetics and diabetes who authored the review together with researcher Tina Rönn.
The researchers detail the latest findings in epigenetics in the following categories: The significance of diet
Quiz on Obesity
There are thousands out there battling ‘the bulge’. With childhood obesity on the rise even children are not spared. If your weight issues are threatening to weigh you down learn more about obesity by taking part in this quiz.
“We are indeed much more than what we eat, but what we eat can nevertheless help us to be much more than what we are”. - Adelle Davis
There are thousands out there battling ‘the bulge’. With childhood obesity on the rise even children are not spared. If your weight issues are threatening to weigh you down learn more about obesity by taking part in this quiz.
Aging
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Diabetes Risk Assessment Calculator
Almost one-third of the people are unaware of the risk factors of diabetes. Find out if you run the risk of diabetes by using Diabetes Risk Assessment calculator.
Almost one-third of the people are unaware of the risk factors of diabetes. Find out if you run the risk of diabetes by using Diabetes Risk Assessment calculator.
Is the epigenome heritable?
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Salk Scientists Tweak CRISPR for Epigenetic Therapies in Diabetes, Kidney Disease and Muscular Dystrophy
A research team at the Salk Institute of Biological Studies, La Jolla has modified CRISPR/Cas9 system to treat diseases like diabetes, kidney disease and muscular dystrophy
A research team at the Salk Institute of Biological Studies, La Jolla has modified CRISPR/Cas9 system to treat diseases like diabetes, kidney disease and muscular dystrophy
Source-Eurekalert
