Peripheral artery disease significantly impacts older adults, causing reduced blood flow, pain, and increased health risks.
Epidemiology and genetic determination of measures of peripheral vascular health in the Long Life Family Study
Go to source).
What is Peripheral Artery Disease
Peripheral artery disease is a common but often undiagnosed condition that affects millions worldwide. It increases the risk of heart disease, stroke, and mobility issues. This study conducted using data from the Long Life Family Study (LLFS), found that individuals from long-lived families have significantly better vascular health than the general population.
Peripheral Artery Disease (PAD)
Peripheral arterial disease is a chronic condition marked by deposition of fatty plaque within arteries of the body and reduction in blood supply.
Peripheral arterial disease is a chronic condition marked by deposition of fatty plaque within arteries of the body and reduction in blood supply.
‘Beyond lifestyle, 4 genomic regions linked to #peripheral_artery_disease (#PAD) risk. #genetics #heartdisease’
The researchers analyzed over 3,000 participants, including 1,090 long-lived individuals, their 1,554 children, and 362 spouses. Among the oldest participants (average age 89), about 18% had PAD. However, among their children (average age 60), only 1% had PAD—far lower than the expected 12% found in other studies. This finding suggests that certain protective factors, whether genetic or lifestyle-related, help maintain healthier arteries in these families. In the study, key risk factors for PAD were identified, including aging, high blood pressure, smoking, and hypertension medication use. Interestingly, unlike in other studies, high cholesterol and diabetes were not major risk factors in this group. This data further supports the idea that long-lived families may have genetic protective factors that contribute to better vascular health.
Three of these were new discoveries, while the fourth was similar but not identical to previously published findings. These genetic markers may help scientists better understand why some individuals are more likely to develop PAD and how to prevent it.
PAD Alert: Marijuana Users are at Risk of Peripheral Artery Disease
Is marijuana bad for your heart? Yes, marijuana use may put you at a higher risk of developing peripheral artery disease (PAD). Check out the impact of marijuana use on health.
Is marijuana bad for your heart? Yes, marijuana use may put you at a higher risk of developing peripheral artery disease (PAD). Check out the impact of marijuana use on health.
This research highlights the value of studying long-lived families to unlock the secrets of healthy aging and vascular health. Understanding what helps them maintain better artery function could lead to new strategies for preventing PAD, heart disease, and other age-related conditions.
Advertisement
Peripheral Artery Disease Indicated By Cramps in The Legs
Peripheral artery disease advances quietly, narrowing blood vessels for years until the supply of nutrients and oxygen falls low enough to cause cramps and leg pain.
Peripheral artery disease advances quietly, narrowing blood vessels for years until the supply of nutrients and oxygen falls low enough to cause cramps and leg pain.
- Epidemiology and genetic determination of measures of peripheral vascular health in the Long Life Family Study - (https://www.aging-us.com/article/206204/text)
Source-Eurekalert
Walk Till it Hurts: Good News for Peripheral Artery Disease Patients
Peripheral artery disease (PAD) is a lifelong medical condition. However, people with PAD can lead active and long lives by walking till their leg hurts.
Peripheral artery disease (PAD) is a lifelong medical condition. However, people with PAD can lead active and long lives by walking till their leg hurts.
