Lyme disease, an infection common in the northwest and northeast parts of the U.S. and caused by bacteria normally found in deer is treated with antibiotics.
Chronic Lyme Disease Remains Immune to Long-Term Antibiotic Treatment
Prolonged antibiotic therapy is not effective in treating patients with Chronic Lyme Disease, who exhibit persistent symptoms.
Prolonged antibiotic therapy is not effective in treating patients with Chronic Lyme Disease, who exhibit persistent symptoms.
‘In addition to knee swelling and pain, both septic arthritis and lyme disease may cause a fever, swelling of other joints, irritability and an inability to bear weight on the affected extremity.’
Septic arthritis is considered a medical emergency requiring surgical irrigation (flushing) and drainage to prevent rapid and irreversible destruction of the cartilage surrounding the knee. Lyme disease, an infection common in the northwest and northeast parts of the U.S. and caused by bacteria normally found in deer and transmitted to humans through ticks, is treated with antibiotics. In addition to knee swelling and pain, both conditions may cause a fever, swelling of other joints, irritability and an inability to bear weight on the affected extremity. Common laboratory tests to measure inflammation, as well as white blood cell counts, also may be elevated. In the new study, researchers reviewed the records of 189 patients under age 18 who presented to Children's Hospital of Philadelphia (CHOP) with excess fluid in the knee between 2005 and 2013. Of these patients, 23 had culture-positive septic arthritis; 26, culture-negative septic arthritis; and 140, Lyme disease.
The study authors found four characteristics that are predictive factors for septic arthritis: knee pain with a short range of motion, a C-reactive protein (CRP test; used to measure inflammation) of >4.0 mg/L, fever, age younger than 2. "The probability of septic arthritis with any one factor present was 18 percent compared to 100 percent will all four factors present," said study author Wudbhav N. Sankar, MD, an orthopaedic surgeon at Children's Hospital of Philadelphia. "Our study offers a useful prediction algorithm to help distinguish septic arthritis from a knee effusion caused by Lyme disease in children."
Big Data and Patient-Powered Research Aim to Solve Chronic Lyme Disease
Over the past forty years, little has been learned about how to prevent, diagnose and effectively treat chronic Lyme disease.
Over the past forty years, little has been learned about how to prevent, diagnose and effectively treat chronic Lyme disease.
Experimental Test Detects Signs of Lyme Disease Early
An experimental method developed by university researchers appears capable of detecting the stealthy culprit Lyme bacteria at the earliest time of infection.
An experimental method developed by university researchers appears capable of detecting the stealthy culprit Lyme bacteria at the earliest time of infection.
New Bacterial Species Identified That Causes Lyme Disease
Patients infected with B. mayonii will test positive for Lyme disease with currently available U.S. Food and Drug Administration-cleared Lyme disease tests.
Patients infected with B. mayonii will test positive for Lyme disease with currently available U.S. Food and Drug Administration-cleared Lyme disease tests.
