Seemingly healthy children have been found to be at increased risk of metabolic disorders, finds a new study. In the study they also found that Waist circumference indicated these disorders more appropriately.
Misfolded Protein Could Trigger Metabolic Disorders
Protein-folding problems are linked with a range of metabolic disorders, though it is unclear if those problems are causes or manifestations of such disorders.
Protein-folding problems are linked with a range of metabolic disorders, though it is unclear if those problems are causes or manifestations of such disorders.
‘Waist circumference measurement was a better indicator of these metabolic changes compared to the currently used body mass index.’
Among 212 children in the study, 26 percent showed abnormal metabolic profiles, including insulin resistance, a sign of type 2 diabetes. Insulin resistance was present in 28 percent of those with overweight or obesity and 5 percent of those with normal weight. Waist circumference was a stronger marker for metabolic alterations than body mass index. "The study that included otherwise healthy full-term children shows that metabolic alterations within the scope of the metabolic syndrome, mostly due to overweight and obesity, are present already in preschoolers. Based on these findings, there is a need to optimize more effective prevention and intervention modalities before obesity is established," said lead author Dr. Emma Kjellberg, of Queen Silvia Children's Hospital, in Sweden.
Source-Eurekalert
Solved Protein Structure Holds Key to Much-Needed Drugs for Metabolic Disorder
There is need for new therapies to combat cognitive dysfunction and psychiatric disorders that arise due to dietary lapses in patients with phenylketonuria.
There is need for new therapies to combat cognitive dysfunction and psychiatric disorders that arise due to dietary lapses in patients with phenylketonuria.
A New Weapon to Treat Rare Metabolic Disorders
The skin color of the flatworm Schmidtea mediterranea changes under prolonged exposure to sunlight, these animals could provide a new model for studying the diseases.
The skin color of the flatworm Schmidtea mediterranea changes under prolonged exposure to sunlight, these animals could provide a new model for studying the diseases.
Maternal Anti-Fetal Brain Autoantibodies Associated with Metabolic Disorders
Diabetic women are three times more likely to have anti-fetal brain autoantibodies, particularly those whose children's autism fell on the severe end of the spectrum.
Diabetic women are three times more likely to have anti-fetal brain autoantibodies, particularly those whose children's autism fell on the severe end of the spectrum.
