In a recent research paper on the effects of alcohol consumption and risks of cardiovascular disease - moderate intake of alcohol associated with reduced risk of heart disease.
Alcohol Use Disorder | Alcoholism
Alcohol use disorder or alcoholism is an inability to control drinking. It can cause short term and long term physical, as well as psychological effects on the patient.
Alcohol use disorder or alcoholism is an inability to control drinking. It can cause short term and long term physical, as well as psychological effects on the patient.
There have been thousands of basic science studies showing that administering alcohol or wine to laboratory animals results in beneficial effects on the risk of atherosclerosis and heart disease. The present excellent paper summarizes what are now a large number of human trials testing whether wine and/or alcohol have the same effects on reducing risk factors for CVD. There have not yet been randomized clinical trials to evaluate the effects of alcohol administration on cardiovascular outcomes such as myocardial infarction, cardiac death, or other cardiovascular diseases (CVD) in humans. It is unlikely that such studies will be done because of the long time of follow up required, the huge cost, and the difficulties in getting a very large number of people randomly assigned to agree to consume a specified amount of alcohol, or agree to avoid all alcohol, for many years. For these lifestyle habits, we must use our best judgment based on carefully done observational studies, research into potential mechanisms of effect, and studies of intermediate outcomes that are in pathways and processes in the development of the disease.
The second paper looked at cohort studies on the association between alcohol consumption and overall mortality from cardiovascular disease, incidence of and mortality from coronary heart disease, and incidence of and mortality from stroke. 4,235 studies were reviewed for eligibility, quality and data extraction, 84 were included in the final analysis.
What is a heart attack / How to prevent heart attacks
Heart attack is the death of the heart muscle due to loss of blood supply. Simple guidelines to avoid heart attack are listed.
Heart attack is the death of the heart muscle due to loss of blood supply. Simple guidelines to avoid heart attack are listed.
The authors concluded that light to moderate alcohol consumption is associated with a reduced risk of multiple cardiovascular outcomes.
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ISFAR members thought that this was a very well done, comprehensive summary of a large number of studies on alcohol and cardiovascular disease. ISFAR welcomed the discussion in the paper as to causality and regarding future directions in research, with more emphasis into how physicians and individual patients might respond to encouragement to consume alcohol for its potentially beneficial effects on cardiovascular disease. Most believe that there is no substitute for balanced judgment by a knowledgeable, objective health professional when discussing alcohol intake, and this requires a synthesis of common sense and the best available scientific facts as they apply to the individual.
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Moderate Drinkers at Higher Risk of Drug Abuse
In a recent research it has been stated that consuming moderate amount of alcohol can increase an individual's risk of amphetamine abuse.
In a recent research it has been stated that consuming moderate amount of alcohol can increase an individual's risk of amphetamine abuse.
The results of this 2011 meta-analysis are in line with what we know from the previous meta-analyses and the many individual studies: risk reductions for alcohol drinkers relative to non-drinkers of 25% for cardiovascular disease mortality, 29% for incident coronary heart disease, 25% for CHD mortality and 13 % for all cause mortality. The lowest risk of CHD mortality occurred with 1-2 drinks (15-30 grams of alcohol) per day is also in line with previous knowledge.
Forum member Erik Skovenborg stated: "The public health messages should (and in many countries do) acknowledge the reduced risk of incidence and mortality of coronary heart disease associated with moderate drinking. However, we should not expect official recommendations of light drinking on a par with exercise, vegetables, and not smoking. The caveats would be too many, and official recommendations should be based on prospective, randomized studies. The role of alcohol drinking is best discussed in a scenario of a patient taking medical advice from his personal physician."
Professor Arthur Klatsky also had pertinent comments on this topic: "In the final section of the paper the authors are struggling with the matter of advice. They are trying to come up with a new angle. We should keep in mind that many practitioners have been interacting with their patients about the benefits of light-moderate drinking for years. An overwhelming majority of persons (at least in our Northern California area) have heard of the benefits of light drinking, with many believing that this is specific for red wine. Some do not believe it as, no doubt, do some practitioners. The emotional baggage many have about alcohol will not go away. For these reasons, my enthusiasm is limited for the authors' suggested approach of 'evaluating the receptivity of both physicians and patients' to recommendations to drink moderately.having practiced cardiology for 50 years, it is clear to me that all advice even upon matters with good evidence needs individualization. With respect to light-moderate drinking, I'll quote the final sentences of my JACC Editorial from 2010: 'The risks of moderate drinking differ by sex, age, personal history, and family history. As is often the case in medical practice, advice about lifestyle must be based on something less than certainty. There is no substitute for balanced judgment by a knowledgeable, objective health professional. What is required is a synthesis of common sense and the best available scientific facts.'
Source-Eurekalert
