The PRAC has recommended restricting Lemtrada for use in adults with relapsing remitting multiple sclerosis that is highly active despite adequate treatment with at least one disease-modifying therapy.
Multiple sclerosis - Symptoms - Causes - Diagnosis - Treatment
Multiple sclerosis can be a severely disabling autoimmune disease that affects the myelin or insulating layer of the nerve fibers and typically has remissions and relapses
Multiple sclerosis can be a severely disabling autoimmune disease that affects the myelin or insulating layer of the nerve fibers and typically has remissions and relapses
‘Immune-mediated conditions can occur many months after treatment while serious disorders of the heart, circulation and bleeding may develop within days of receiving Lemtrada.’
The PRAC has recommended restricting Lemtrada for use in adults with relapsing remitting multiple sclerosis that is highly active despite adequate treatment with at least one disease-modifying therapy or if the disease is worsening rapidly with at least two disabling relapses in a year and brain-imaging showing new damage. Also, Lemtrada must no longer be used in patients with certain heart, circulation or bleeding disorders or in patients who have auto-immune disorders other than multiple sclerosis. New measures have been recommended for identifying and promptly dealing with adverse effects that might occur after treatment with Lemtrada. It should be given in a hospital with ready access to intensive care facilities and specialists who can manage serious adverse reactions.
The PRAC has also recommended updating the physician’s guide and the patient information pack with advice to minimise the risk of serious heart, circulation and bleeding disorders that may occur shortly after the infusion (drip) as well as autoimmune conditions that could occur many months after the last Lemtrada treatment.
Quiz on Multiple Sclerosis
Multiple sclerosis is an autoimmune disease that affects nerves and can leave the affected patient completely disabled. Test your knowledge on this condition by taking this quiz.
Multiple sclerosis is an autoimmune disease that affects nerves and can leave the affected patient completely disabled. Test your knowledge on this condition by taking this quiz.
The PRAC recommendations will now be sent to EMA’s human medicines committee (CHMP), which will adopt the Agency’s final opinion.
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Alemtuzumab
Alemtuzumab is a cancer-treating drug used for treating certain cancers of bone marrow and blood cancers such as chronic lymphocytic leukemia (CLL) and lymphoma. It is a monoclonal antibody used to treat multiple sclerosis.
Alemtuzumab is a cancer-treating drug used for treating certain cancers of bone marrow and blood cancers such as chronic lymphocytic leukemia (CLL) and lymphoma. It is a monoclonal antibody used to treat multiple sclerosis.
Unemployment in Multiple Sclerosis People Vary by Age: Study
New study explores various factors that contribute to the high unemployment rate among people of different ages with multiple sclerosis (MS).
New study explores various factors that contribute to the high unemployment rate among people of different ages with multiple sclerosis (MS).
