A new series of chemical combinations that suppress severe lung inflammation has been discovered by scientists.
Using Traditional Biomass Stoves can Cause Lung Inflammation
Traditional cookstoves that use biomass materials which are widely used in developing nations where cooking is done indoors have been shown to cause lung inflammation like COPD, reports a new study.
Traditional cookstoves that use biomass materials which are widely used in developing nations where cooking is done indoors have been shown to cause lung inflammation like COPD, reports a new study.
‘The results of the study will provide new safe drugs to combat viral diseases. Primarily with severe influenza and COVID-19.’
Specialists from the UrFU have created a method for the synthesis of new chemical compounds. They contain azoloazine heterocycles, substances that can inhibit the activity of interleukin-6. This is a group of molecules that play an important role in the immune response. However, according to scientists, in some cases, an excess of interleukin causes uncontrolled inflammation, tissue destruction and threatens the lives of patients. New compounds will help contain this dangerous reaction.
Lung Inflammation
“In general, the direction of our research is more fundamental, but we can create an applied product based on this knowledge. Thanks to our initial fundamental research, a number of medicines have already entered the pharmaceutical market,” says Konstantin Savateev, a researcher at the Laboratory of Organic Synthesis of UrFU.The therapeutic effect of heterocycles was confirmed by specialists from the Volgograd State Medical University. They observed experimental animals and carried out histological studies of their lungs. The mice were injected with new compounds and a special toxin that caused inflammation. The same occurs with severe lung damage, the scientists noted.
Currently, the substance dexamethasone is used in medicine. It depresses the immune system, which in some cases is an undesirable side effect. The new compounds show anti-inflammatory effects on the level of dexamethasone, but do not suppress immunity.
Test your Knowledge on Coronavirus (COVID-19)
Coronavirus is a large positive-strand RNA virus that is surrounded by a protein envelope. The virus obtains its name from the S protein spikes on its surface, which resemble a crown. The overall pattern of increasing coronavirus cases is shown to spike up with the “second wave” of COVID-19.
With spiking effects of the second wave of coronavirus, the best way to keep it at bay is to follow COVID-appropriate safety practices like wearing a mask, regularly cleaning your hands, and coughing into a bent elbow or tissue along with physical distancing (6 feet about 2 arm's length), that may help evade the severity of COVID-19 infection.
Coronavirus is a large positive-strand RNA virus that is surrounded by a protein envelope. The virus obtains its name from the S protein spikes on its surface, which resemble a crown. The overall pattern of increasing coronavirus cases is shown to spike up with the “second wave” of COVID-19.
With spiking effects of the second wave of coronavirus, the best way to keep it at bay is to follow COVID-appropriate safety practices like wearing a mask, regularly cleaning your hands, and coughing into a bent elbow or tissue along with physical distancing (6 feet about 2 arm's length), that may help evade the severity of COVID-19 infection.
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