A breakthrough in cancer studies after using novel technology to reveal the different genetic patterns of neuroblastoma, an aggressive form of childhood cancer, has been reached by researchers.
A breakthrough in cancer studies after using novel technology to reveal the different genetic patterns of neuroblastoma, an aggressive form of childhood cancer, has been reached by researchers.
Two research teams led by professors Tommy Martinsson, of the Sahlgrenska Academy at the University of Gothenburg, Sweden and Per Kogner of Karolinska Institutet monitored children with neuroblastoma, a nerve cell cancer that has defects in certain chromosomes, for over 20 years.
Targeted Therapy for Neuroblastoma on the Anvil After Detection of Genetic Glitch
A genetic glitch responsible for the development of the fatal childhood cancer, neuroblastoma, has been identified by scientists from University of Florida.
A genetic glitch responsible for the development of the fatal childhood cancer, neuroblastoma, has been identified by scientists from University of Florida.
Boffins were able to successfully analyze the DNA of tumor cells and identify chromosomal defects with the use of latest genetic techniques, enabling the identification of sub-groups of the most aggressive neuroblastomas.
Martinsson, professor of genetics at the Department of Clinical Genetics, said: "We call this personalized medicine, because the treatment is based on the genetic profile of the patient, or in this case, of the tumour cells."
Therapeutic Targets for Neuroblastoma Identified
Scientists have identified potential therapeutic targets for the treatment of neuroblastoma, the most frequent solid tumour in young children.
Scientists have identified potential therapeutic targets for the treatment of neuroblastoma, the most frequent solid tumour in young children.
Carén added: "The analytical method we have used in our research is already being used for clinical assessment of every neuroblastoma tumor in the country, which means that we can now make more accurate diagnoses."
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Long-Term Health and Social Outcomes for Neuroblastoma Survivors
Survivors of the childhood cancer neuroblastoma are eight times more likely to have chronic health conditions, less likely to be married, and more likely to have lower incomes than
Survivors of the childhood cancer neuroblastoma are eight times more likely to have chronic health conditions, less likely to be married, and more likely to have lower incomes than
Source-ANI
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Metastasis of Neuroblastoma linked to Loss Of Caspase-8 gene
The caspase-8 gene prevents the metastasis of the neuroblastoma.
The caspase-8 gene prevents the metastasis of the neuroblastoma.
