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New Non-allergenic, Anti-inflammatory Fragrance Could be Game-changer for Dry Skin Sufferers

by Iswarya on Oct 31 2020 4:08 PM

Novel allergen-depleted and anti-inflammatory fragrance can be used in moisturizers for people with extremely dry, xerotic skin.

New Non-allergenic, Anti-inflammatory Fragrance Could be Game-changer for Dry Skin Sufferers
Novel allergen-depleted and anti-inflammatory fragrance can be used in moisturizers for people with extremely dry, xerotic skin. The findings of the study are presented at the 29th EADV Congress.
Tests on skin cells found that the allergen-depleted fragrance composition's anti-inflammatory ingredients reduced the expression of both Prostaglandin E2 and Interleukin-8 after applying a stressor substance.

The researchers also studied the fragrance formulated in a moisturizer applied to human volunteers' forearms after they shaved their skin on three consecutive days to induce skin irritation. They found that skin redness was significantly reduced in the skin treated with the moisturizer.

Fragrances are moisturizers, the most frequent causes of allergic contact dermatitis. The novel fragrance was developed without using any of the 26 commonly known allergens and without the additional 60+ potential allergens currently under evaluation.

However, it still has a pleasant scent, improving the metic acceptability rating and, consequently, enhancing patients' treatment adherence.

Dr. Julia Gallinger, a senior scientist at Beiersdorf AG's Research and Development department: "A moisturiser containing our novel fragrance could provide an improved treatment option for people with dry skin conditions. It would be both pleasant to use due to its scent, enhancing patients` treatment adherence, and actively soothe inflammation. Hence, the long-standing paradigm of fragranced moisturisers considered as allergenic risk in the treatment of xerotic dermatoses may soon become obsolete. The fragrance has been integrated into two new Eucerin UreaRepair PLUS products for dry skin to provide skin care with a pleasurable experience."

Also, a patient preference study among 86 people with dry skin who used the fragranced moisturizer for two weeks showed that 97% agree that it doesn't just feel like they have to apply something on their skin, but now they also enjoy it. 91% confirmed that the scented lotion makes their care routine more pleasant. Furthermore, 71% confirmed that they like the scented product better than the unscented moisturizer they normally use.

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Source-Eurekalert


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