Modern cancer therapy aims to develop drugs which can target the altered tumor cells in every patient, without affecting the healthy cells.
Amino Acid for Brain Cancer Therapy
Brain tumors are often treated by photodynamic therapy,because of its specificity.It can target very small regions containing cancerous cells while sparing the normal cells around it from damage.
Brain tumors are often treated by photodynamic therapy,because of its specificity.It can target very small regions containing cancerous cells while sparing the normal cells around it from damage.
‘New targeted cancer therapy has identified an inhibitor that limits the growth of tumor cells by exhibiting a fusion of the proteins BRD4 and NUT.’
Scientists in the working groups of Professor Roman Thomas and Professor Martin Sos at the Institute of Pathology and the Department of Translational Genomics of Cologne University Hospital have tested the effects of more than 1,500 substances on different kinds of cancer cells. The testing procedure was carried out in cooperation with the Technical University of Dortmund, the Lead Discovery Center Dortmund, and other international groups.
The researchers were able to identify an inhibitor that specifically limits the growth of cells exhibiting a fusion of the proteins BRD4 and NUT.
Why Anti-cancer Therapy Stops Working at a Specific Stage
At the Hebrew University of Jerusalem and in California, researchers have achieved a breakthrough in understanding how and why a promising anti-cancer therapy has failed to achieve hoped-for success in killing tumor cells.
At the Hebrew University of Jerusalem and in California, researchers have achieved a breakthrough in understanding how and why a promising anti-cancer therapy has failed to achieve hoped-for success in killing tumor cells.
In the study, the scientists were able to shed light on the molecular mechanism responsible for the effectiveness of the inhibitor. Their insights are an important prerequisite for the development of new and improved therapies for NMC, which is lethal in most cases.
Advertisement
Key to Personalized Cancer Therapy - Metabolic Profiles
Metabolic profiling will be essential for defining each cancer and choosing the best treatment accordingly, the researchers say.
Metabolic profiling will be essential for defining each cancer and choosing the best treatment accordingly, the researchers say.
Source-Eurekalert
New Methodology may Revolutionize Breast Cancer Therapy
Stroma cells are derived from connective tissue and may critically influence tumour growth. The knowledge about this is not new.
Stroma cells are derived from connective tissue and may critically influence tumour growth. The knowledge about this is not new.
