African children in coma still face deadly odds—with little improvement despite advances in malaria control.

The aetiologies, mortality, and disability of non-traumatic coma in African children: a systematic review and meta-analysis
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Hidden Burden: Coma in African Children
A study published in The Lancet Global Health reveals that the death rate due to malaria infection in African children has remained unchanged for nearly fifty years, with nearly one in every five children dying. This is the largest analysis of febrile non-traumatic coma in African children to date.Advertisement
Mortality and Disability That Refuse to Shift
A Malawi study reveals cerebral malaria is the leading cause of febrile coma, with over 25% complicated by co-infections. Children with malaria and bacterial meningitis are more likely to die. The study calls for urgent re-consideration of frontline management and immediate antibiotics.Way Forward
The University of Liverpool's study highlights the importance of molecular and radiological diagnostics in managing life-threatening brain infections, highlighting the need for coordinated strategies and investment.References:
- The aetiologies, mortality, and disability of non-traumatic coma in African children: a systematic review and meta-analysis- (https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(25)00055-5/fulltext)
Source-Eurekalert