One Hour Everyday Older Adults With Type 1 Diabetes Have Low Blood Sugar

Low blood sugar unawareness in older adults with type 1 diabetes could put them at risk of seizures, loss of consciousness and death, finds a new study.

For more than an hour a day older adults with type 1 diabetes typically have low blood sugar, finds a new study. The results of this study are going to be presented at ENDO 2019, the annual meeting of the Endocrine Society, in New Orleans, La on Monday, March 25.

Those who are not aware their blood sugar is too low can spend more than 100 minutes a day in the hypoglycemic range, raising their risk of seizures, loss of consciousness and death.

One Step Closer to Prevent Life-threatening Episodes of Low Blood Sugar in Diabetics: Study
Novel biomarker might help create a diagnostic tool for hypoglycemia-associated autonomic failure (HAAF) which can prevent life-threatening episodes of low blood sugar in diabetics.

‘If blood sugar falls below a healthy range and is not treated, it can be dangerous. It can lead to blurred vision, difficulty concentrating, confused thinking, slurred speech, numbness, and drowsiness.’

Until now, there has been limited data on how much time older adults with type 1 diabetes spend in the hypoglycemic range, according to lead researcher Anders L. Carlson, M.D., Medical Director of the International Diabetes Center in Minneapolis, Minn.

"This study of older individuals shows these patients do indeed spend more than an hour per day in a range of hypoglycemia, which puts them at risk for the dangers of low blood glucose," Carlson said. "Those who do not sense when low blood glucose is occurring as strongly as others can are particularly at risk."

Low blood sugar can lead to blurred vision, difficulty concentrating, confused thinking, slurred speech, numbness and drowsiness.

Novel Biomarker Might Help Prevent Critical Episodes of Low Blood Sugar with Diabetes
Hypoglycemia (low blood sugar) associated autonomic failure, or HAAF can be prevented by creating a diagnostic tool with the help of new biomarker.

If blood sugar falls below a healthy range and is not treated, it can be dangerous. Severe hypoglycemia is treated with an injection of the hormone glucagon. Severe untreated hypoglycemia can cause seizures, loss of consciousness and death.

Many people with type 1 diabetes have low blood sugar but experience no symptoms, a condition called hypoglycemia unawareness. Because they don't know when their blood sugar is low, they don't know they need to treat it. This puts them at risk for severe hypoglycemia events, which requires another person to help them recover. They also are less likely to be awakened from sleep.

Comparison of Types of Insulin for Reducing Episodes of Low Blood Sugar for Patients
Reduced rate of hypoglycemic (low blood sugar) episodes resulted from treatment with the insulin degludec compared to glargine U100 for 32 weeks

The study reflects baseline data as part of a randomized clinical trial that included 203 adults age 60 and older with type 1 diabetes who used a continuous glucose monitor for up to 21 days. The monitor automatically tracks blood sugar levels throughout the day and night. A continuous glucose monitor uses alarms to alert patients when blood glucose levels are low or start to fall quickly.

"The findings underscore the need for interventions to help reduce the risk of severe hypoglycemia in this age group," Carlson said.

Dextrose Gel Reduces Risk of Low Blood Sugar in Newborns
Nearly one in three infants is at risk for neonatal hypoglycaemia (low blood sugar levels), which raise a baby's risk of impaired nervous system development.

Source-Eurekalert