Trans-chalcone prevents the survival of bacteria in oral cavities that cause the formation of plaque and acid which lead to tooth decay.
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Researchers said, "Blocking the activity of the enzyme prevents bacteria forming a protective biological layer – known as a biofilm – around themselves. Plaque is formed when bacteria attach themselves to teeth and construct biofilms. Preventing the assembly of these protective layers would help stop bacteria forming plaque. Oral care products that contain similar natural compounds could help people improve their dental hygiene."
Team leader Dominic Campopiano said, "We are expanding the study to include similar natural products and investigate if they can be incorporated into consumer products. This exciting discovery highlights the potential of this class of natural products in food and healthcare technologies."
The study appears in Chemical Communications.
Source-Medindia