For treating a range of conditions such as cancer, inflammatory diseases and age-related macular degeneration, inhibiting the formation of new blood vessels is a common strategy.
Daily Exercise can Ease Drug-Related Joint Pain in Breast Cancer Patients
Women being treated with breast cancer drugs known as aromatase inhibitors can markedly ease the joint pain associated with the drugs by engaging themselves in moderate daily exercise.
Women being treated with breast cancer drugs known as aromatase inhibitors can markedly ease the joint pain associated with the drugs by engaging themselves in moderate daily exercise.
While current strategies to thwart pathological blood vessel formation focus primarily on inhibiting vascular endothelial growth factor (VEGF), this latest research centers around blocking glycolysis, the process that endothelial cells rely on for generating most of the energy they need to multiply and migrate. Endothelial cells form the inner lining of a blood vessel and provide a barrier between the vessel wall and blood.
Dr. Carmeliet and his team previously found that the glycolytic activator PFKFB3 promotes blood vessel formation by stimulating glycolysis in endothelial cells. In their new work, the investigators discovered that blocking PFKFB3 with a small molecule called 3PO reduced blood vessel sprouting by inhibiting the proliferation and movement of endothelial cells.
People Usually Quit Smoking When Celebs Promote Cancer Screening
A new study suggests that while the start of a new year looks like a promising way to start off on a clean slate by quitting bad habits, it may not be as much of a powerful motivator as the motivation of a celebrity.
A new study suggests that while the start of a new year looks like a promising way to start off on a clean slate by quitting bad habits, it may not be as much of a powerful motivator as the motivation of a celebrity.
The findings could lead to new treatments that block the excessive blood vessel growth that supports cancer spread, causes blindness, and fuels inflammatory diseases such as psoriasis and inflammatory bowel disease.
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No Clear Link Between Lung Cancer and Passive Smoke, Reveals Study
A recent study reveals passive smoking has no clear link to lung cancer.
A recent study reveals passive smoking has no clear link to lung cancer.
Early-Stage Breast Cancer Patients Undergo Unnecessary Imaging Procedures
A new research from the University of Texas revealed how more than one-third of early-stage breast cancer patients go unnecessary imaging procedures
A new research from the University of Texas revealed how more than one-third of early-stage breast cancer patients go unnecessary imaging procedures
