Poor Sleep Quality in Children Associated With Rise in BMI

Improper sleep is associated with with higher body mass index in children, which can increase cancer risk.

Several measures of poor sleep quality were associated higher body mass index (BMI) in children, which puts them at greater risk for obesity-related cancers during adulthood, according to data presented at the American Association for Cancer Research Special Conference Obesity and Cancer: Mechanisms Underlying Etiology and Outcomes.

About one in five children between the ages of 6 and 19 is obese, according to recent statistics from the Centers for Disease Control and Prevention. The percentage of U.S. children with obesity has more than tripled since the 1970s, with significant immediate and long-term effects.

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‘Shorter sleep duration in children was found to be associated with a higher body mass index.’

"Childhood obesity very often leads to adult obesity," said the study's lead author, Bernard Fuemmeler, PhD, MPH, professor and associate director for cancer prevention and control at Virginia Commonwealth University's Massey Cancer Center. "This puts them at greater risk of developing obesity-related cancers in adulthood."

Fuemmeler explained that previous research has shown that sleep patterns play a role in obesity in adults, but most research exploring the connection between sleep and obesity in children has focused on the duration of sleep, rather than the way quality of sleep or circadian patterns affect eating behaviors and weight.

Study overview

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In this study, Fuemmeler and colleagues enrolled 120 children whose mothers had participated in the Newborn Epigenetic Study, a federally funded project that examines how environmental exposures and nutrition, both pre-birth and during early childhood, affect how genes work. The average age of the children was 8. Researchers controlled for age, sex, race, and maternal education as an indicator of socioeconomic status.

To track the sleep-wake cycle, the children wore accelerometers continuously for 24 hours per day for a period of at least five days. To gauge eating habits, children completed the "eating in the absence of hunger test." Children ate a meal and reported when they were full; the researchers then tracked how much food they ate once they had reached the point of satiety.

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The researchers found:

• Shorter sleep duration, measured in hours, was associated with a higher BMI z-score (body mass index adjusted for age and sex). Each additional hour of sleep was associated with a .13 decrease in BMI z-score, and with a 1.29 centimeter decrease in waist circumference.

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• More fragmented rest-activity rhythms and increased intradaily variability, a measure of the frequency and extent of transitions between sleep and activity, were also associated with greater waist circumferences.

• Earlier onset of the most active period during daytime, diurnal activity, was associated with higher intake of calories once the children had reached the point of satiety.

Overall, Fuemmeler said, the study results indicate that while sleep duration is important, examining markers of sleep quality may also be useful in designing childhood obesity prevention strategies.

"Today, many children are not getting enough sleep," Fuemmeler said. "There are a number of distractions, such as screens in the bedroom, that contribute to interrupted, fragmented sleep. This, perpetuated over time, can be a risk factor for obesity. Because of the strong links between obesity and many types of cancer, childhood obesity prevention is cancer prevention, in my view."

Fuemmeler said that while further research is necessary to understand more about the way poor sleep affects weight, families would benefit from following guidelines established by the American Academy of Pediatrics.

The study's primary limitation is that it did not include prospective data that might have helped researchers assess whether sleep quality influences weight gain or weight in children affects their sleep. Fuemmeler said that data will be encompassed in future studies.

Source-Eurekalert