Targeting mitochondrial translation pathways could be a successful treatment strategy for triple-negative breast cancer.
Breast Cancer - Prevention and Management with Lifestyle Changes
Lifestyle choices may or may not cause breast cancer but healthy lifestyle changes can open up avenues beyond breast cancer. Good habits will allow one to fight breast cancer and to live with dignity.
Lifestyle choices may or may not cause breast cancer but healthy lifestyle changes can open up avenues beyond breast cancer. Good habits will allow one to fight breast cancer and to live with dignity.
‘Certain drugs work by inhibiting mitochondrial protein translation and reducing the growth of TNBC tumors.’
In this issue of the JCI, a team led by Eldad Zacksenhaus at Toronto General Research Institute discovered that the growth of TNBC-like breast tumors is supported by enhanced mitochondrial function. Mice carrying tumors that were deficient in both RB1 and p53 displayed upregulation of a pathway that controls the synthesis of mitochondrial proteins.
They then identified an FDA-approved drug, tigecycline, that blocks this upregulation and reduces the growth of TNBC-like tumors in mice.
Artificial Intelligence Software Expedites Efficient prediction of Breast Cancer Risk
A new artificial intelligence software can scan mammograms and in a short time determine breast cancer risk and prevents false-positives and biopsies.
A new artificial intelligence software can scan mammograms and in a short time determine breast cancer risk and prevents false-positives and biopsies.
Source-Medindia
High Blood Pressure Drugs may Slow the Growth of Triple Negative Breast Cancer
Beta blockers, a commonly prescribed class of high blood pressure drugs, may have the potential to slow the growth of triple negative breast cancer tumors.
Beta blockers, a commonly prescribed class of high blood pressure drugs, may have the potential to slow the growth of triple negative breast cancer tumors.
Quiz on Breast Cancer
Breast cancer is one of the leading causes of cancer deaths among women. It is often said that a woman who breast-feeds is at a lower risk of developing cancer compared to another who does not .Are these mere old wives tales or is there some truth in it? This quiz on breast cancer has all the details.
Breast cancer is one of the leading causes of cancer deaths among women. It is often said that a woman who breast-feeds is at a lower risk of developing cancer compared to another who does not .Are these mere old wives tales or is there some truth in it? This quiz on breast cancer has all the details.
