New research highlights how BMI patterns during midlife affect the likelihood of bone fractures in old age.

Association of bone fracture with 30-year body mass index (BMI) trajectories: findings from the Framingham Heart Study
Go to source). The study, "Association of bone fracture with 30-year body mass index (BMI) trajectories: findings from the Framingham Heart Study," provides valuable insights into the potential implications of BMI changes on fracture risk later in life.
‘Did You Know?
The average BMI has increased globally over the past few decades, contributing to rising rates of obesity-related diseases. #bodymassindex #bmi #adulthood’

The study analyzed data from the Framingham Original Cohort Study, involving 1772 participants with an average follow-up of 17.1 years. The average BMI has increased globally over the past few decades, contributing to rising rates of obesity-related diseases. #bodymassindex #bmi #adulthood’





BMI trajectories were constructed using latent class mixed modeling, and their association with fracture risk after age 65 was explored using Cox regression.
BMI-Bone Fracture Connection
Key findings of the study include:- Participants transitioning from overweight to normal weight during middle adulthood had a higher risk of all fractures after age 65 years compared to those who maintained a stable BMI.
- Similar patterns were observed for lower extremity fractures, including pelvis, hip, leg, and foot fractures.
"For overweight individuals, strategies to avoid bone loss during periods of weight loss during middle adulthood could be beneficial in terms of reducing fracture risk. This is especially true with the recent increases in the use of the new obesity drugs. "
Reference:
- Association of bone fracture with 30-year body mass index (BMI) trajectories: findings from the Framingham Heart Study - (https://link.springer.com/article/10.1007/s00198-024-07068-7)
Source-Eurekalert