Promising New Therapeutic Approach to Treat Lazy Eye Disorder

A research team has used the popular puzzle video game Tetris in an innovative approach to treat adult amblyopia, commonly known as lazy eye .

A research team has used the popular puzzle video game Tetris in an innovative approach to treat adult amblyopia, commonly known as "lazy eye".

The team was led by Dr. Robert Hess from McGill University and the Research Institute of the McGill University Health Centre (RI-MUHC).

Children With Amblyopia Need Not Wear Eye Patches All Day: Study
A new research has revealed that children with amblyopia, commonly known as Lazy Eye, don’t need to wear their eye patches the entire day.

By distributing information between the two eyes in a complementary fashion, the video game trains both eyes to work together, which is counter to previous treatments for the disorder (e.g. patching).

This medical breakthrough provides direct evidence that alleviating suppression of the weaker eye, by forcing both eyes to cooperate, increases the level of plasticity in the brain and allows the amblyopic brain to relearn. The research is published in the prestigious journal Current Biology.

Amblyopia is the most common cause of visual impairment in childhood, affecting up to 3 per cent of the population. It is caused by poor processing in the brain, which results in suppression of the weaker eye by the stronger eye. Previous treatments for the disorder, which have focused largely on covering the stronger eye in order to force the weaker eye to work, have proven only partially successful in children and have been ineffective in adults.

Changes in Subcortical Regions of Brain may Cause Abnormal Involuntary Eye Movements in Amblyopia
Despite the special role of eye movements in vision, scientists have not been able to find out much about oculomotor function in amblyopia, or lazy eye, .

"The key to improving vision for adults, who currently have no other treatment options, was to set up conditions that would enable the two eyes to cooperate for the first time in a given task," says Dr. Robert Hess, senior author of the paper and Director of Research Department of Ophthalmology at the RI-MUHC and at McGill University.

According to Dr. Hess and his colleagues, the adult human brain has a significant degree of plasticity and this provides the basis for treating a range of conditions where vision has been lost as a result of a disrupted period of early visual development in childhood. The researchers examined the potential of treating amblyopic adults using the video game Tetris, which involves connecting different shaped blocks as they fall to the ground.

All-inclusive, Accessible Vision Testing Device Developed by University Of Tennessee Researchers
Vision contributes to eighty-five percent of children's learning. Still, 80 percent of children in the U.S. have never had an eye exam or any vision screening prior to kindergarten, note statistics.

"Using head-mounted video goggles we were able to display the game dichoptically, where one eye was allowed to see only the falling objects, and the other eye was allowed to see only the ground plane objects," explains Dr. Hess, who also serves as director of McGill Vision Research. "Forcing the eyes to work together, we believed, would improve vision in the lazy eye."

The researchers tested a sample of 18 adults with amblyopia. Nine participants played the game monocularly with the weaker eye, while the stronger eye was patched; the other nine played the same game dichoptically, where each eye was allowed to view a separate part of the game. After two weeks, the group playing the dichoptic game showed a dramatic improvement in the vision of the weaker eye as well as in 3-D depth perception. When the monocular patching group, who had showed only a moderate improvement, was switched to the new dichoptic training, the vision of this group also improved dramatically.

Video Game Treatment Could Help Correct 'Lazy Eye'
Playing video games along with standard treatment can help fix amblyopia, also called lazy eye in older children, finds study.

The suitability of this treatment in children will be assessed later this year in a clinical trial across North America.

Source-Eurekalert