Silencing the expression of protein called RAB27A resulted in reduced metastasis -- the process by which cancer spreads to other areas of the body -- which is the primary cause of death in melanoma patients.
Melanoma - Causes, Symptoms, Diagnosis, Treatment & Prevention
Melanoma of the skin is a dangerous type of skin cancer that usually appears as a cancerous mole due to exposure to the sun’s damaging UV rays.
Melanoma of the skin is a dangerous type of skin cancer that usually appears as a cancerous mole due to exposure to the sun’s damaging UV rays.
‘RAB27A is a novel prognostic factor which means it could provide clinicians with a new way to determine a melanoma patient's future health outcome.’
While there have been recent advances in targeted and immune-based treatments, advanced stage melanoma remains a clinical challenge with a particularly poor prognosis, suggests the study published in the International Journal of Cancer. "We also believe it could provide a brand new therapeutic target for the prevention of metastasis, which would improve the efficacy of future treatments", Guo added.
According to the researchers, Australia and New Zealand have the highest rates of melanoma in the world. More than 14,000 new cases of melanoma are estimated to have occurred in 2018.
Test your Knowledge on Moles and Melanoma
Melanoma is a skin condition that is often a consequence of excessive exposure to the sun’s ultraviolet radiation. Test your knowledge on melanoma by taking this quiz.
Melanoma is a skin condition that is often a consequence of excessive exposure to the sun’s ultraviolet radiation. Test your knowledge on melanoma by taking this quiz.
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Three Treatment Strategies for Malignant Melanoma
Study finds evidence that combining three advanced treatment strategies for malignant melanoma - molecular targeted therapy, immune checkpoint blockade and the use of tumor-targeting viruses - may markedly improve outcomes.
Study finds evidence that combining three advanced treatment strategies for malignant melanoma - molecular targeted therapy, immune checkpoint blockade and the use of tumor-targeting viruses - may markedly improve outcomes.
New Drug Combination Is More Effective For Melanoma
Protein kinase inhibitors combined with ribonuclease compounds reduce the incidence of various side effects and prevent the emergence of drug-resistant melanoma
Protein kinase inhibitors combined with ribonuclease compounds reduce the incidence of various side effects and prevent the emergence of drug-resistant melanoma
