Race and Genetics Linked With Development of Food Allergies Among Children

A child’s sensitivity to developing allergies to specific foods is linked with race and the role played by his genes, according to a new study conducted by researchers at Henry Ford Hospital. Researchers found:

• African-American children were sensitized to at least one food allergen three times more often than Caucasian children.
• African-American children with one allergic parent were sensitized to an environmental allergen twice as often as African-American children without an allergic parent.
  
  
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  The study will be presented Saturday at the American Academy of Allergy, Asthma and Immunology annual meeting, "Our findings suggest that African Americans may have a gene making them more susceptible to food allergen sensitization or the sensitization is just more prevalent in African American children than white children at age 2," says Haejim Kim, M.D., a Henry Ford allergist and the study's lead author. "More research is needed to further look at the development of allergy."Sensitization means a person's immune system produces a specific antibody to an allergen.
  
  It does not mean the person will experience allergy symptoms.According to an AAAI study from 2009-2010, an estimated 8 percent of children have a food allergy, and 30 percent of children have multiple food allergies. Peanut is the most prevalent allergen, followed by milk and shellfish.1The Henry Ford study consisted of a longitudinal birth cohort of 543 children who were interviewed with their parents and examined at a clinical visit at age 2. Data included parental self-report of allergies and self-reported race (African American or white/non-Hispanic). The children were skin-tested for three food allergens – egg whites, peanuts and milk – and seven environmental allergens.
  
  Key findings:
  • 20.1 percent of African-American children were sensitized to an food allergen compared to 6.4 percent in Caucasian children.
  • 13.9 percent of African-American children were sensitized to an environmental allergen compared to 11 percent of Caucasian children.
  • African-American children with an allergic parent were sensitized to an environmental allergen 2.45 times more often than African-American children without an allergic parent.
  
  
  
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