Dementia - Types, Causes, Symptoms, Diagnosis, Treatment
Dementia has become a very big concern as we have an aging population across the world. Dementia is also terrifying to us because of its disturbing symptoms and limited treatment options.
Dementia has become a very big concern as we have an aging population across the world. Dementia is also terrifying to us because of its disturbing symptoms and limited treatment options.
‘cis P-tau mAb reversed 85% to 90 % of the severe clinical features of dementia.
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The study was performed by researchers from the Medical University of South Carolina (MUSC) and Beth Israel Deaconess Medical Center (BIDMC), Harvard Medical School. The team observed signs of brain inflammation and memory loss in a pre-clinical model of vascular dementia (VaD) and severe cognitive impairment in a separate pre-clinical model of Alzheimer's disease (AD). A toxic, non-degradable version of a healthy brain protein called cis P-tau was associated with both cases. When treating the mice (pre-clinical models) with the monoclonal antibody (mAb) cis P-tau mAb, the team obtained promising outcomes in preventing clinical features like neural degradation and cognitive decline.
The changes caused by the accumulation of cis P-tau protein in the genetic architecture of the VaD model were also consistent with those seen in human AD patients.
Test Your Knowledge on Dementia
Dementia is a leading cause of disability in older people. It is a condition where brain cells are permanently damaged or functionally impaired. Till 2015, about 47.5 million people suffer from dementia across the globe. There are various conditions that lead to dementia and it is important to get aware of its causes, effects and vulnerability. So how much do you know dementia? Take our advanced quiz and learn!
Dementia is a leading cause of disability in older people. It is a condition where brain cells are permanently damaged or functionally impaired. Till 2015, about 47.5 million people suffer from dementia across the globe. There are various conditions that lead to dementia and it is important to get aware of its causes, effects and vulnerability. So how much do you know dementia? Take our advanced quiz and learn!
"We believe our findings have not only discovered cis P-tau as a previously unrecognized major early driver of VaD and AD but also identified a highly effective and specific immunotherapy to target this common disease driver for treating and preventing AD and VaD at early stages," said Onder Albayram, Ph.D., co-lead author and assistant professor in the Division of Cardiology in the Department of Medicine at MUSC.
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Processed Meat May Increase Dementia Risk
Increased risk of developing dementia is potentially linked to the consumption of processed meat such as bacon, sausages, and burger.
Increased risk of developing dementia is potentially linked to the consumption of processed meat such as bacon, sausages, and burger.
CDC Suggests Vaccinated Persons Not to Remove Masks
New guideline for vaccinated individuals does not grant permission for widespread removal of masks, the US Centers of Disease Control and Prevention (CDC) Director Rochelle Walensky said.
New guideline for vaccinated individuals does not grant permission for widespread removal of masks, the US Centers of Disease Control and Prevention (CDC) Director Rochelle Walensky said.
