Spontaneous Orthogonal Alignment of Smooth Muscle Cells and Endothelial Cells Captures Native Blood Vessel Morphology in Tissue-Engineered Vascular Grafts
Go to source). By combining multiple materials and fabrication technologies, the team from University of Melbourne developed the method to create blood vessels with complex geometries like native blood vessels.
The Vital Role of Blood Vessels in Sustaining Health
Blood vessels serve an important function in sustaining life, by carrying oxygen-rich blood and essential nutrients to all parts of the body while removing toxic products. Illness and dysfunction in blood vessels, on the other hand, can result in life-threatening disorders such as heart attacks, strokes and aneurysms, making cardiovascular disease the number one killer globally.
Kawasaki Disease
Kawasaki disease affects the children that involve the skin, mouth and blood vessels. It can be treated with acetaminophen, aspirin and intravenous gamma globulin.
Kawasaki disease affects the children that involve the skin, mouth and blood vessels. It can be treated with acetaminophen, aspirin and intravenous gamma globulin.
‘The tissue-engineered blood vessels, composed of human cells and tissues, hold the potential for treating cardiovascular conditions and establishing a built-in blood supply for larger tissue constructs. #bloodvessels’
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According to Professor Andrea O’Connor, from the Department of Biomedical Engineering, the research is an exciting step in scientists’ ability to engineer human blood vessels. “We are now able to rapidly and cheaply manufacture blood vessels using living tissue that has appropriate mechanical properties and mimics the cellular orientation of the innermost layer of blood vessels.
“While the engineered blood vessels are not yet ready for bypass surgery, the findings mark a significant advancement in the field of tissue engineering,” O’Connor said, in the paper published in the journal ACS Applied Materials and Interfaces.
Angiogenesis
Angiogenesis is the process of formation of new blood vessels from pre-existing blood vessels. It occurs both in health as well as disease.
Angiogenesis is the process of formation of new blood vessels from pre-existing blood vessels. It occurs both in health as well as disease.
“Current methods are slow, require specialized and expensive equipment like bioreactors, and are low throughput -- meaning it’s difficult to provide the needed supply of engineered vessels,” Associate Professor Heath said.
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Blood Vessels Can Kill Cancer Cells and Stop Breast Cancer Spread
New study highlights the dual role that blood vessels can play in cancer immunotherapy and eliciting anti-tumor immune responses or even preventing breast cancer spread.
New study highlights the dual role that blood vessels can play in cancer immunotherapy and eliciting anti-tumor immune responses or even preventing breast cancer spread.
- Spontaneous Orthogonal Alignment of Smooth Muscle Cells and Endothelial Cells Captures Native Blood Vessel Morphology in Tissue-Engineered Vascular Grafts - (https://pubs.acs.org/doi/10.1021/acsami.3c08511)
Visualizing the 3D View of Build-up of Fats on Blood Vessel Wall
Visualization of atherosclerotic plaques in blood vessel walls by combining magnetic resonance imaging (MRI) and mathematical analysis to define features.
Visualization of atherosclerotic plaques in blood vessel walls by combining magnetic resonance imaging (MRI) and mathematical analysis to define features.
