Scientists at Wistar Institute have identified a gene called KLF17, which appears to be involved in the spread of breast cancer throughout the body.
Scientists at Wistar Institute have identified a gene called KLF17, which appears to be involved in the spread of breast cancer throughout the body.
"Identifying the gene that suppresses the spread of tumor cells and the mechanisms by which this suppression occurs can lead to the discovery of new markers of metastasis and potential targets for cancer prevention and treatment," Nature quoted Dr Qihong Huang, assistant professor at The Wistar Institute and senior author of the study as saying.
Scientists Identify Protein That Supports Aggressive Breast Cancer Growth
A protein may be required for some of the most aggressive forms of breast cancer to grow, Fox Chase Cancer Center researchers have demonstrated.
A protein may be required for some of the most aggressive forms of breast cancer to grow, Fox Chase Cancer Center researchers have demonstrated.
Through RNA interference (RNAi) technology, they then reduced the expression of a metastasis-suppressor gene in five mice, one of which developed lung metastases in seven weeks. RNA retrieved from the metastasized cells corresponded to KLF17.
The researchers also were interested specifically in genes whose expression were increased in KLF17 knockdown cells but decreased in KLF17 overexpressing cells or vice versa. They found the significant genes that met these criteria.
Breast Cancer Risk is Reduced by Vigorous Exercise
Researchers writing the open access journal BMC Cancer have revealed that post-menopausal women who engage in moderate to vigorous exercise have a reduced risk of breast cancer.
Researchers writing the open access journal BMC Cancer have revealed that post-menopausal women who engage in moderate to vigorous exercise have a reduced risk of breast cancer.
The study showed that that expression of KLF17 together with Id1gene accurately predicts whether the disease will spread to the lymph nodes.
Advertisement
Social Isolation Hastens Breast Cancer Growth: Study
A socially isolated, stressful environment can speed up breast cancer growth, says a new study.
A socially isolated, stressful environment can speed up breast cancer growth, says a new study.
Source-ANI
ARU
