Spanish Woman Infected With Omicron Just 20 Days After Delta

Fully vaccinated 31-year-old Spanish woman tested positive for Omicron variant in just 20 days after having Delta infection of COVID-19.

A 31-year-old Spanish woman who was tested positive for COVID-19 twice within three weeks, reveal researchers.

The case report being presented at this year’s European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Lisbon, Portugal.

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‘The Spanish woman was fully vaccinated and therefore, was partially protected against severe Covid-19 infection and hospitalization.’

The 20-day gap between infections is the shortest known.

The woman, a healthcare worker, first tested positive on December 20, 2021, in a PCR test during staff screening at her place of work.

She had been fully vaccinated and had received a booster shot too 12 days earlier.

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The patient, who didn’t develop any symptoms, self-isolated for 10 days before returning to work.

On January 10, 2022, just 20 days after first testing positive, she developed a cough and a high fever and felt generally unwell and did another PCR test. This was also positive.

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Whole-genome sequencing showed that patient had been infected by two different strains of SARS-CoV-2. Their first infection, in December, was with the Delta variant. The second, in January, was with the Omicron variant.

The Omicron variant had been identified as a variant of concern by the World Health Organization just over a month earlier, on November 26, 2021.

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The strain, which went on to become the dominant variant worldwide, is much more infectious than Delta and can evade immunity from past infections and from vaccination.

Dr. Gemma Recio, of Institut Català de Salut, Tarragona, Spain, one of the study’s authors, says: “This case highlights the potential of the Omicron variant to evade the previous immunity acquired either from natural infection with other variants or from vaccines."

“In other words, people who have had COVID-19 cannot assume they are protected against reinfection, even if they have been fully vaccinated."

“Nevertheless, both previous infection with other variants and vaccination do seem to partially protect against severe disease and hospitalization in those with Omicron."

“This case also underscores the need to carry out genomic surveillance of viruses in infections in those who are fully vaccinated and in reinfections. Such monitoring will help detect variants with the ability to partially evade the immune response.”

Source-Eurekalert