Transference-focused psychotherapy was associated with activation of increases in cognitive control areas and relative decreases in areas related to emotional reactivity.

‘Patients with Borderline Personality Disorder have problems regulating emotions and thoughts. An estimated 1.6 percent of the U.S. population is affected by the behavioral health issue.’

These patients were treated for one year with transference-focused psychotherapy (TFP), an evidence-based treatment proven to reduce symptoms across multiple cognitive-emotional domains in BPD. Treatment with TFP was associated with relative activation increases in cognitive control areas and relative decreases in areas associated with emotional reactivity. According to researchers, these findings suggest that TFP may potentially facilitate symptom improvement in BPD. 




"These findings represent the genuine frontier of clinical science in understanding the effects of psychotherapy," said Lenzenweger. "Think of it -- talk therapy that impacts neural or brain functioning."
"These results advance our currently limited understanding of neural mechanisms associated with psychodynamically oriented psychotherapy," wrote the researchers. "Activation in [certain parts of the brain] was associated with improvements in behavioral constraint, emotional regulation and/or aggression in patients with BPD."
The study, "Frontolimbic neural circuit changes in emotional processing and inhibitory control associated with clinical improvement following transference-focused psychotherapy in borderline personality disorder," was published in Psychiatry and Clinical Neurosciences.
Source-Eurekalert