Stop Diseased Dental Implants With Expert Immune Cells

Preventive implant maintenance using machine learning algorithm to quantify the harmful bacteria and certain infection fighting immune cells for individuals reduce the risk of Peri-implantitis.

Peri-implantitis is condition where tissue and bone around dental implants becomes infected lead to progressive bone loss, bleeding, pus and eventual loss of the dental implants. There is no conventional method to avert this condition and predict their prognosis.

Patients who were at low risk for periodontal disease showed more immune cells that were highly adept at controlling bacterial infections, said Yu Leo Lei, senior author and assistant professor of dentistry.

Periodontitis| Gingivitis - Causes Risk Factors Symptoms Diagnosis Treatment
Periodontitis or pyorrhea is infection and inflammation of ligament tissues that surround and support the teeth. Periodontitis causes loss of alveolar bones leading to loosening and loss of teeth.

‘Adroit Immune cells forecast Diseased Dental Implants.’

To address this issue, team led by the University of Michigan School of Dentistry developed a machine learning algorithm, FARDEEP (Fast and Robust Deconvolution of Expression Profiles) - a form of artificial intelligence to find out competent patient for regenerative outcomes after surgical treatments of peri-implantitis.

"Regenerative therapy for peri-implantitis is expensive and treatment outcomes are unpredictable," said first author Jeff Wang, U-M clinical assistant professor and principal investigator for the regenerative treatment of peri-implantitis clinical trial.

In designing the algorithm more emphasis is given to identify the immune cell types capable of wound healing and tissue repair for microbial control correlate with superior clinical outcome.

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Though FARDEEP decides the personalized old implant replacement option for regenerative therapy for peri-implantitis, more human clinical trials are required to be used by clinicians.

Dental Check-Up
It is commonly recommended that you visit the dentist twice a year to clean your teeth and gums and also do the basic check–ups.

Source-Eurekalert

Loose Teeth - Causes - Symptoms - Treatment - FAQs
Looseness of teeth is caused by a disease of the periodontium and includes the tissues surrounding the teeth.