Using high-throughput genomics researchers have identified rare highly-penetrant genetic variants that drive the development of gestational diabetes.
Gestational Diabetes About
The condition is not caused by a lack of insulin, but by the action of hormones produced during pregnancy that blocks the action of insulin.
The condition is not caused by a lack of insulin, but by the action of hormones produced during pregnancy that blocks the action of insulin.
‘Pregnancy-induced diabetes has a strong underlying genetic element that interacts with lifestyle factors and the physiologic changes accompanying pregnancy to alter maternal glucose regulation.’
The mechanisms causing gestational diabetes are complex and incompletely understood. The study, entitled 'Screening for monogenic subtypes of gestational diabetes in a high prevalence island population - a whole exome sequencing study' provides the first description of atypical diabetes presenting in pregnancy in the Maltese population.
This research integrates clinical medicine, genomics and protein modelling with longitudinal follow-up data. The paper highlights the genetic heterogeneity underlying disorders of glucose regulation and reinforces the role of precision medicine research in unravelling the aetiology of complex traits.
Quiz on Gestational Diabetes
Gestational diabetes occurs in women during pregnancy when blood glucose levels increase in their body. It is diagnosed during the 24th week of pregnancy. Take this quiz to know more about its complications and how will your baby get affected if its left untreated.
Gestational diabetes occurs in women during pregnancy when blood glucose levels increase in their body. It is diagnosed during the 24th week of pregnancy. Take this quiz to know more about its complications and how will your baby get affected if its left untreated.
Serious Consequences of Gestational Diabetes on Fetal Growth
Gestational diabetes (diabetes during pregnancy), an independent risk factor for fetal hypoxia during labor can be monitored using intensified Cardiotocography (CTG) for early prevention.
Gestational diabetes (diabetes during pregnancy), an independent risk factor for fetal hypoxia during labor can be monitored using intensified Cardiotocography (CTG) for early prevention.
Gestational Diabetes Predicts the Onset of Type-1 or Type-2 Diabetes
Gestational diabetes during pregnancy is shown to be strongly associated with the emergence of type-1 and type-2 diabetes later in life.
Gestational diabetes during pregnancy is shown to be strongly associated with the emergence of type-1 and type-2 diabetes later in life.
