Kids who develop a rare Kawasaki-like inflammatory syndrome after witnessing COVID recover within three months.
About Kawasaki Disease
Kawasaki disease affects the children that involve the skin, mouth and blood vessels. It can be treated with acetaminophen, aspirin and intravenous gamma globulin.
Kawasaki disease affects the children that involve the skin, mouth and blood vessels. It can be treated with acetaminophen, aspirin and intravenous gamma globulin.
‘Kawasaki alike condition is triggered by an overreaction in the immune system to fight off a COVID infection and sees the body attack healthy cells.’
MIS-C, also known as pediatric inflammatory multisystem syndrome (PIMS), causes swelling throughout the body, including around vital organs such as the heart. Some children also developed Kawasaki-like multisystem inflammatory conditions, including a high temperature, rash, tiredness, and stomach pain. In rare cases, some children may require intensive care.
Researchers from the University of Pennsylvania conducted a study of 120 children -- half of whom were hospitalized with MIS-C and found they all had normal heart function within a week, Daily Mail reported.
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Coronavirus is a large positive-strand RNA virus that is surrounded by a protein envelope. The virus obtains its name from the S protein spikes on its surface, which resemble a crown. The overall pattern of increasing coronavirus cases is shown to spike up with the “second wave” of COVID-19.
With spiking effects of the second wave of coronavirus, the best way to keep it at bay is to follow COVID-appropriate safety practices like wearing a mask, regularly cleaning your hands, and coughing into a bent elbow or tissue along with physical distancing (6 feet about 2 arm's length), that may help evade the severity of COVID-19 infection.
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"Our findings may also provide guidance for a gradual return to playing sports after cardiac clearance three to four months later," he added.
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The children, who were mostly boys and aged 10 on average, were treated with intravenous immunoglobulin -- an antibody treatment that helps fight off infection -- or corticosteroids, which calm down the immune system.
Then they compared the findings to a control group of 60 children who did not have COVID or heart problems.
While all the MIS-C patients' heart function improved quickly within the first week, even patients with "significant cardiac abnormalities" saw their changes resolved within three months.
Seven percent of the hospitalized children had some heart malfunction when first admitted, but this had disappeared three months later.
Eight in 10 patients lost some contractile function -- the ability of the heart to contract and pump blood -- when they were most unwell, but three to four months later, this had also returned to normal, the report said.
And the condition did not cause any long-lasting problems in the coronary arteries, which are responsible for supplying blood to the heart.
But the researchers warned MIS-C and COVID are still new illnesses, so it is yet to be determined if sufferers' hearts have any problems beyond four months after they were diagnosed with heart problems, the report said.
Source-IANS
