Jörg Kleeff from Technische Universität München, and colleagues suggest that patients with apparently locally non-resectable tumors should be included in neoadjuvant protocols.
Jörg Kleeff from Technische Universität München, and colleagues suggest that patients with apparently locally non-resectable tumors should be included in neoadjuvant protocols. Thei research is published this week in PLoS Medicine.
The authors systematically reviewed studies concerning the effects of neoadjuvant therapy on tumor response, toxicity, resection, and survival percentages in pancreatic cancer.
Pancreatic Cancer - All About the Disease, its Diagnosis and Management
Pancreatic cancer often involves its exocrine part. It grows aggressively, and often detected late. Treatment options include surgery, radiation and chemotherapy.
Pancreatic cancer often involves its exocrine part. It grows aggressively, and often detected late. Treatment options include surgery, radiation and chemotherapy.
The authors examined 111 studies, involving 4,394 patients, and found that a third of patients initially judged unresectable were able to undergo resection after neoadjuvant therapy. These patients were then found to have a similar survival rate to patients judged resectable before neoadjuvant treatment (the average survival time being 20.5 months after resection). Although randomized trials are now needed to confirm this finding, they suggest that patients presenting with locally advanced/unresectable tumors should be offered neoadjuvant therapy and then re-evaluated for resection.
Cancer Pain - Causes - Effects - Assessment - Treatment - FAQs - Video
Every 1 out of 3 people undergoing cancer treatment experiences pain.
Every 1 out of 3 people undergoing cancer treatment experiences pain.
RAS
About Cancer in Women
Cancer is one of the frequently talked about and most feared disease that falls under the genre of lifestyle diseases that have evolved, rather rapidly, in the past two decades.
Cancer is one of the frequently talked about and most feared disease that falls under the genre of lifestyle diseases that have evolved, rather rapidly, in the past two decades.
