Faster Monkeypox (mpox) Testing Through CRISPR
Go to source). The study utilized a genetic sequence combined with a reporter, and programmable CRISPR RNA targeted the mpox virus. The CRISPR/Cas12a cleaved the reporter, generating fragments analyzed with nanopore sensing technology, offering a swift and precise test for detecting mpox presence.
Monkeypox
Monkeypox infection is a zoonotic viral infection that usually lasts for 3 weeks. It is caused by the monkeypox virus and is characterized by rash or pox-like symptoms.
Monkeypox infection is a zoonotic viral infection that usually lasts for 3 weeks. It is caused by the monkeypox virus and is characterized by rash or pox-like symptoms.
‘CRISPR offers a faster testing method for detecting monkeypox, soon adaptable to any clinic setting. #mpox #monkeypox #CRISPR’
Md. Ahasan Ahamed, a graduate student mentored by Weihua Guan at Pennsylvania State University will present this research at the 68th Biophysical Society Annual Meeting, to be held February 10 - 14, 2024 in Philadelphia, Pennsylvania.
Understanding Mpox: Importance of Testing for Timely Detection
Though mpox symptoms are generally mild with fever, rash, and swollen lymph nodes, severe cases can occur and require medical attention. Because the disease is contagious, testing is important so that people with the disease can isolate until symptoms resolve or get appropriate medical care.The team confirmed that the test they created is specific to mpox—when they tested samples of cowpox virus, a close relative of mpox, the test did not show a positive result.
The whole process is quick, “in total it takes 32 to 55 minutes to detect the target, depending on viral load,” Ahamed said, which is much faster than it currently takes to test for mpox in a lab using PCR method.
Test Your Knowledge on Monkeypox
Introduction: Monkeypox is a rare viral infection caused by the monkeypox virus, which belongs to the same family of smallpox. It typically occurs in central and western Africa. Sometimes, small clusters or isolated infections are ...
Introduction: Monkeypox is a rare viral infection caused by the monkeypox virus, which belongs to the same family of smallpox. It typically occurs in central and western Africa. Sometimes, small clusters or isolated infections are ...
Reference:
- Faster Monkeypox (mpox) Testing Through CRISPR - (https://www.biophysics.org/news-room?ArtMID=802&ArticleID=14925&preview=true)
Source-Eurekalert
Monkeypox Outbreak Extends Across Five Indonesian Provinces
The viral infection of monkeypox has now spread to five provinces in Indonesia, said authorities.
The viral infection of monkeypox has now spread to five provinces in Indonesia, said authorities.
Growing Monkeypox Outbreak in Indonesia Prompts Heightened Alert
Indonesia's Health Ministry is on high alert due to 14 confirmed monkeypox cases since its first detection on October 13.
Indonesia's Health Ministry is on high alert due to 14 confirmed monkeypox cases since its first detection on October 13.
