Researchers from University of Pennsylvania School of Medicine have identified a potential therapeutic target for maintaining healthy blood pressure.
A potential therapeutic target that researchers from the University of Pennsylvania School of Medicine have identified may prove handy in maintaining healthy blood pressure.
In the study conducted using mouse model, the team discovered that mice lacking the receptor for one type of prostaglandin, a family of fatty compounds key to the cardiovascular system, have lower blood pressure and less atherosclerosis.
High Blood Pressure
High blood pressure or hypertension is defined as a blood pressure of above 140 mm Hg (systolic) and or 90mm Hg (diastolic).
High blood pressure or hypertension is defined as a blood pressure of above 140 mm Hg (systolic) and or 90mm Hg (diastolic).
"Blocking this prostaglandin receptor may provide a strategy for controlling blood pressure and its attendant vascular disease," said senior author Dr Garret A. FitzGerald, Director of the Institute for Translational Medicine and Therapeutics at Penn.
The delicate balance the body maintains to keep blood pressure stable involves not only the prostaglandin system, but another biological pathway, the renin-angiotensin-aldosterone system, or RAAS.
High Dietary Intake Of Salt Ups Hypertension, Stroke Risk
Increased dietary intake of salt, more than the recommended intake of 2.8 g for active young people and 2.2 for older adults, pose a high risk to hypertension and strokes.
Increased dietary intake of salt, more than the recommended intake of 2.8 g for active young people and 2.2 for older adults, pose a high risk to hypertension and strokes.
"The picture is emerging that PGF2a controls blood pressure by a mechanism unique among the prostaglandins," said FitzGerald.
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Low Lead Levels in Early Childhood Linked to Hypertension in Later Life
Researchers from State University of New York have found that low levels of lead found in the blood during early childhood can increase a child's risk of developing hypertension in later life.
Researchers from State University of New York have found that low levels of lead found in the blood during early childhood can increase a child's risk of developing hypertension in later life.
Source-ANI
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