Treating Blood Pressure to Lower Than Recommended Levels Reduces Risk for Heart Attack

High blood pressure, which affects an estimated one-in-three Americans is the leading risk factor for heart disease, stroke and kidney failure.

Bringing down your systolic blood pressure to current recommended levels may reduce risk for heart attack, hear failure and stroke, says a new study.

The research, which applies to adults age 50 and older, showed that risk of heart attack, heart failure and stroke was reduced by nearly a third, and death by almost a quarter, when patients were asked to bring down their systolic blood pressure below what is currently recommended.

Reduction in Systolic Blood Pressure Below 140 is Important in Primary Stroke Prevention
People 60 or older, especially minorities and women, have a lower risk of stroke if their systolic blood pressure is below 140 millimeters of mercury (mm Hg).

Recommendations for systolic blood pressure -- the greater of the two numbers that measure blood pressure -- currently indicate that patients should aim for less than 140 mm Hg.

The researchers, however, adjusted participants' blood pressure medication to achieve a target systolic pressure of 120 mm Hg.

"This study provides potentially lifesaving information that will be useful to health care providers as they consider the best treatment options for some of their patients, particularly those over the age of 50," said Gary Gibbons, director of the National Heart, Lung, and Blood Institute (NHLBI), the main sponsor of the clinical trial.

Lowering Systolic Blood Pressure Below Normal Provides No Benefit for High Blood Pressure Patients
Researchers at Wake Forest Baptist Medical Center suggest that the traditional treatment of lowering the systolic blood pressure below 120 mm of Hg provides no additional benefit for patients.

Initial results were so convincing that the NHLBI halted the study well before its 2017 end date, so it could publish the research.

"We are delighted to have achieved this important milestone in the study in advance of the expected closure date," said Gibbons.

'Mild' Systolic BP Control Good Enough for Adults Above 65
A mild control of systolic blood pressure should be fine for adults age 65 or older, a new research reveals.

High blood pressure -- which affects an estimated one-in-three Americans -- is the leading risk factor for heart disease, stroke, kidney failure and a slew of other problems, said the study.

"Our results provide important evidence that treating blood pressure to a lower goal in older or high-risk patients can be beneficial and yield better health results overall," said Lawrence Fine, head of NHLBI's clinical applications and prevention branch.

Blood Biomarkers Help Predict Heart Failure Risk
A simple model developed by researchers uses age, race and two blood biomarkers to predict heart failure risk.

The trial began in late 2009 with more than 9,300 participants 50 years and older, recruited at hundreds of medical centers across the United States and Puerto Rico.

The study is the largest clinical trial to date to examine the effects of hypertension treatment targeting systolic blood pressure at a level below current recommendations.

Source-AFP