Plant-based diet or vegan diet may enhance gut bacteria associated with diabetes risk factors such as body weight, body composition, and blood sugar control, reveals a new study.
Eating a vegetarian or plant-based diet may enhance gut bacteria associated with diabetes risk factors such as body weight, body composition, and blood sugar control, reports a new study.// New research presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) in Barcelona, Spain (16-20 Sept) suggests that a 16-week vegan diet can boost the gut microbes that are related to improvements in body weight, body composition and blood sugar control. The study is by Dr Hana Kahleova, Physicians Committee for Responsible Medicine (PCRM), Washington, DC, USA, and colleagues.
‘Just eating a plant-based diet for 16 weeks can boost the gut microbes that are related to improvements in body weight, body composition and blood sugar control.’
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Gut microbiota play an important role in weight regulation, the development of metabolic syndrome, and type 2 diabetes. The aim of this study was to test the effect of a 16-week plant-based diet on gut microbiota composition, body weight, body composition, and insulin resistance in overweight adults with no history of diabetes.Read More..
The study included 147 participants (86% women and 14% men; mean age was 55.6±11.3 years), who were randomized to follow a low-fat vegan diet (n=73) or to make no changes to their diet (n=74) for 16 weeks. At baseline and 16 weeks, gut microbiota composition was assessed, using uBiome kits. Dual energy X-ray absorptiometry was used to measure body composition. A standard method called the PREDIM index was used to assess insulin sensitivity.
Following the 16-week study, body weight was reduced significantly in the vegan group (treatment effect average -5.8 kg), particularly due to a reduction in fat mass (average -3.9 kg) and in visceral fat. Insulin sensitivity also increased significantly in the vegan group.
The relative abundance of Faecalibacterium prausnitzii increased in the vegan group (treatment effect +4.8%). Relative changes in Faecalibacterium prausnitzii were associated with decreases in body weight, fat mass and visceral fat. The relative abundance of Bacteoides fragilis also increased in the vegan group (treatment effect +19.5%). Relative changes in Bacteroides fragilis were associated with decreases in body weight, fat mass and visceral fat, and increases in insulin sensitivity.
The authors conclude: "A 16-week low-fat vegan dietary intervention induced changes in gut microbiota that were related to changes in weight, body composition and insulin sensitivity in overweight adults."
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They add: "The main shift in the gut microbiome composition was due to an increased relative content of short-chain fatty acid producing bacteria that feed on fiber. Therefore, high dietary fiber content seems to be essential for the changes observed in our study. We plan to compare the effects of a vegan and a standard portion-controlled diet on gut microbiome in people with type 2 diabetes, in order to separate out the positive effects of the reduced calories in the diet from those caused by the vegan composition of the diet."
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The authors say that fiber is the most important component of plant foods that promotes a healthy gut microbiome. Faecalibacterium prausnitzii is one of the short-chain fatty acids producing bacteria, which degrade plant complex sugars and starch to produce health-promoting butyrate and/or other short-chain fatty acids that have been found to have a beneficial effect on body weight, body composition, and insulin sensitivity. The authors say: "Eating more fiber is the number one dietary recommendation for a healthy gut microbiome."
Source-Eurekalert