New Way to Reverse Memory Loss in Alzheimer's Patients

In the brains of Alzheimer's patients, genes that are required to form new memories are shut down by a genetic blockade, contributing to cognitive decline. A research team from the Massachusetts Institute of Technology have found a way to reverse memory loss by interfering with the enzyme that forms the blockade.

blocking the activity of an enzyme linked to alzheimer's marks reverse memory loss
- HDAC2 is a key regulator of learning and memory
- HDAC2 inhibitors block other class of HDAC, leading to toxic side effects
- blocking the HDAC2s interaction with a binding partner called Sp3 can reverse memory

New Way to Reverse Memory Loss in Alzheimer's Patients

A genetic blockade in the brains of the Alzheimer's patients causes memory loss. Memory can be reversed by interfering with a HDAC2 enzyme that forms the blockade. Read More

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