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| Abbreviation | Expansion |
| I&D | Incision and drainage |
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| I&O | Intake and output |
| I:E | Inspiratory to Expiratory ratio |
| IABP | Intra-Aortic Balloon Pump |
| IAP | Intermittent Acute Porphyria |
| IBC | Iron Binding Capacity |
| IBD | Inflammatory Bowel Disease |
| IBS | Irritable Bowel Syndrome |
| IBW | Ideal Body Weight |
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| ICA | Internal Carotid Artery |
| ICCE | Intracapsular Cataract Extraction |
| ICF | Intermediate Care Facility, Intracellular Fluid |
| ICP | Intracranial Pressure |
| ICS | Intercostal Space |
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| ICSH | Interstitial Cell Stimulating Hormone |
| ICT | Inflammation of Connective Tissue |
| ICU | Intensive Care Unit |
| IDDM | Insulin Dependent Diabetes Mellitus |
| IDM | Infant of Diabetic Mother |
| IDU | Injection Drug User, Injecting Drug User |
| IE | Inspiratory Exerciser |
| IGF | Insulinlike Growth Factor |
| IH | Infectious Hepatitis |
| IHD | Ischemic Heart Disease |
| IHSS | Idiopathic Hypertropic Subaortic Stenosis |
| IIP | Implantable Insulin Pump |
| IM | Intramuscular |
| IMV | Intermittent Mandatory Ventilation |
| INF | Intravenous Nutritional Fluid |
| INN | International Nonpropritary Names |
| INR | International Normalization Ratio |
| IOF | International Operation Forces |
| IPAP | Inspiratory Positive Airway Pressure |
| IPD | Intermittent Peritoneal Dialysis |
| IPPB | Intermittent Positive Pressure Breathing |
| IPPV | Intermittent Positive Pressure Ventilation |
| IPV | Inactivated Poliovirus Vaccine |
| IQ | Intelligence Quotient |
| IRBBB | Incomplete Right Bundle Branch Block |
| IRDM | Insulin Resistant Diabetes Mellitus |
| ITP | Immune Thrombocytopenic Purpura |
| IUCD | Intrauterine Contraceptive Device |
| IUD | IntraUterine Device |
| IV | Intravenous |
| IVC | Intravenous Cholangiogram or Inferior Vena Cava |
| IVDA | IV Drug Abuse/Abuser |
| IVDP | Intervertebral Disc Prolapase |
| IVF | In Vitro Fertilization |
| IVH | Intraventricular hemorrhage |
| IVIG | Intravenous Immunoglobulin |
| IVP | Intravenous Pyelography |
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